The Surgical and Systemic Management of Neuroendocrine Tumors of the Pancreas

被引：45

作者：

Abood, Gerard J.

Go, Aileen ^{[2
]}

Malhotra, Deepak ^{[2
]}

Shoup, Margo ^{[1
]}

机构：

[1] Loyola Univ, Med Ctr, Dept Gen Surg, Div Surg Oncol, Maywood, IL 60153 USA

[2] Loyola Univ, Med Ctr, Div Hematol & Oncol, Cardinal Bernardin Canc Ctr, Maywood, IL 60153 USA

来源：

SURGICAL CLINICS OF NORTH AMERICA | 2009年 / 89卷 / 01期

关键词：

Neuroendocrine tumor; Surgical resection; Metastatic neuroendocrine tumor; Surgical intervention; ISLET-CELL TUMORS; ZOLLINGER-ELLISON-SYNDROME; SOMATOSTATIN-RECEPTOR SCINTIGRAPHY; MULTIPLE ENDOCRINE NEOPLASIA; HEPATIC ARTERIAL EMBOLIZATION; PHASE-II TRIAL; LIVER METASTASES; PREOPERATIVE LOCALIZATION; LONG-TERM; GASTROENTEROPANCREATIC TUMORS;

D O I：

10.1016/j.suc.2008.10.001

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Neuroendocrine tumors of the pancreas comprise a class of rare tumors that can be associated with symptoms of hormone overproduction. Five distinct clinical endocrinopathies are associated with neuroendocrine tumors; however, most of these tumors remain asymptomatic and follow an indolent course. Complete surgical resection offers the only hope for cure, but understanding the basic biology of the tumors has advanced the medical management in metastatic disease. Surgical resection of hepatic metastases offers survival advantage and should be performed when feasible. Although hepatic artery embolization is currently the preferred mode of nonsurgical palliation for pain and hormonal symptoms, other modalities may play a role in metastatic disease.

引用

页码：249 / +

页数：19

共 123 条

[1] Analysis of factors associated with longterm (five or more years) cure in patients undergoing operation for Zollinger-Ellison syndrome - Discussion [J].