Peptide antibiotics in action: Investigation of polypeptide chains in insoluble environments by rotational-echo double resonance

被引：26
作者：
Toke, Orsolya
Cegelski, Lynette
Schaefer, Jacob
机构：
[1] Washington Univ, Dept Chem, St Louis, MO 63130 USA
[2] Hungarian Acad Sci, Inst Struct Chem, Chem Res Ctr, H-1025 Budapest, Hungary
[3] Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 2006年 / 1758卷 / 09期
关键词：
host-defense peptides; ion-channels; membrane pores; vancomycin; oritavancin; cell wall; solid state NMR; dipolar recoupling;
D O I：
10.1016/j.bbamem.2006.02.031
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Rotational-echo double resonance (REDOR) is a solid-state NMR technique that has the capability of providing intra- and intermolecular distance and orientational restraints in non-crystallizable, poorly soluble heterogeneous molecular systems such as cell membranes and cell walls. In this review, we will present two applications of REDOR: the investigation of a magainin-related antimicrobial peptide in lipid bilayers and the study of a vancomycin-like glycopeptide in the cell walls of Staphylococcus aureus. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码：1314 / 1329
页数：16
相关论文
共 111 条
[1]  
ANDERSON JS, 1967, J BIOL CHEM, V242, P3180
[2]   NUCLEAR MAGNETIC RESONANCE SPECTRA FROM A CRYSTAL ROTATED AT HIGH SPEED [J].
ANDREW, ER ;
BRADBURY, A ;
EADES, RG .
NATURE, 1958, 182 (4650) :1659-1659
[3]  
[Anonymous], 1990, PRINCIPLES MAGNETIC, DOI DOI 10.1007/978-3-662-09441
[4]  
[Anonymous], 2002, MMWR MORB MORTAL WKL, V51, P565
[5]   Correlation experiments for assignment and structure elucidation of immobilized polypeptides under magic angle spinning [J].
Baldus, M .
PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, 2002, 41 (1-2) :1-47
[6]   THE STRUCTURE AND MODE OF ACTION OF GLYCOPEPTIDE ANTIBIOTICS OF THE VANCOMYCIN GROUP [J].
BARNA, JCJ ;
WILLIAMS, DH .
ANNUAL REVIEW OF MICROBIOLOGY, 1984, 38 :339-357
[7]   The structure, dynamics and orientation of antimicrobial peptides in membranes by multidimensional solid-state NMR spectroscopy [J].
Bechinger, B .
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1999, 1462 (1-2) :157-183
[8]   STRUCTURE AND ORIENTATION OF THE ANTIBIOTIC PEPTIDE MAGAININ IN MEMBRANES BY SOLID-STATE NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY [J].
BECHINGER, B ;
ZASLOFF, M ;
OPELLA, SJ .
PROTEIN SCIENCE, 1993, 2 (12) :2077-2084
[9]   CHEMICAL-SHIFT CORRELATION SPECTROSCOPY IN ROTATING SOLIDS - RADIO FREQUENCY-DRIVEN DIPOLAR RECOUPLING AND LONGITUDINAL EXCHANGE [J].
BENNETT, AE ;
OK, JH ;
GRIFFIN, RG ;
VEGA, S .
JOURNAL OF CHEMICAL PHYSICS, 1992, 96 (11) :8624-8627
[10]  
BENNETT AE, 1994, NMR-B PR PR, V33, P1
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