Preparation and characterization of silica-supported magnetic nanocatalyst and application in the synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives

Silica-supported magnetic nanoparticles were simply prepared in high yields and characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, X-ray diffraction, transmission electron microscopy, and energy-dispersive X-ray spectroscopy analyses. Then, Fe3O4@SiO2 core-shell was used as a reusable and efficient heterogeneous nanocatalyst in a one-pot three-component condensation of various aromatic aldehydes, malononitrile, and 1,3-dicarbonyl compounds to yield 2-amino-4-aryl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile derivatives as worthy structures under mild reaction conditions and easy workup procedure.