Effect of the crossing-structure sequence on mixing performance within three-dimensional micromixers

被引:29
作者
Feng, Xiangsong [1 ]
Ren, Yukun [1 ]
Jiang, Hongyuan [1 ]
机构
[1] Harbin Inst Technol, Sch Mechatron Engn, Harbin 150001, Peoples R China
关键词
DEVICE; MIXER;
D O I
10.1063/1.4881275
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The geometry of crossing structure formed by two-layer microchannels determines the axial and transverse movements of contact interface between two liquid streams, which gives us a new method for promoting the micromixers. Hence, we designed four different three-dimensional micromixers by selecting two different crossing structures as basic units (one unit is a crossing structure called "X" and the other is a reversed crossing structure called "rX"). In order to find out how the crossing-structure sequence affects the mixing performance within three-dimensional micromixers, we organized these four mixers in different ways, i.e., the first combination is X-rX-X-rX-..., the second is X-rX-rX-X-..., the third is X-X-rX-X-..., and the last one is X-X-X-X.... Consequently, quite distinct mixing phenomena are engendered. Furthermore, experiments were also conducted using the first and the last models to verify the simulation results. We infer that the last mixer is more likely to trigger chaos and convection by rotating the contact surface than the first one that merely swings the surface even when the flow rates and viscosities of the two liquid streams are increased. (C) 2014 AIP Publishing LLC.
引用
收藏
页数:7
相关论文
共 28 条
[1]   Ultrasonic agitation in microchannels [J].
Bengtsson, M ;
Laurell, T .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2004, 378 (07) :1716-1721
[2]   Optimization of an electrokinetic mixer for microfluidic applications [J].
Bockelmann, Hendryk ;
Heuveline, Vincent ;
Barz, Dominik P. J. .
BIOMICROFLUIDICS, 2012, 6 (02)
[3]   Topologic mixing on a microfluidic chip [J].
Chen, H ;
Meiners, JC .
APPLIED PHYSICS LETTERS, 2004, 84 (12) :2193-2195
[4]   Analysis of chaos and FRET reaction in split-and-recombine microreactors [J].
Chen, Yu-Tzu ;
Fang, Wei-Feng ;
Liu, Yen-Cheng ;
Yang, Jing-Tang .
MICROFLUIDICS AND NANOFLUIDICS, 2011, 11 (03) :339-352
[5]   A simplified design of the staggered herringbone micromixer for practical applications [J].
Du, Yan ;
Zhang, Zhiyi ;
Yim, ChaeHo ;
Lin, Min ;
Cao, Xudong .
BIOMICROFLUIDICS, 2010, 4 (02)
[6]   An effective splitting-and-recombination micromixer with self-rotated contact surface for wide Reynolds number range applications [J].
Feng, Xiangsong ;
Ren, Yukun ;
Jiang, Hongyuan .
BIOMICROFLUIDICS, 2013, 7 (05)
[7]   Polymer-based device for efficient mixing of viscoelastic fluids [J].
Gan, Hiong Yap ;
Lam, Yee Cheong ;
Nguyen, Nam-Trung .
APPLIED PHYSICS LETTERS, 2006, 88 (22)
[8]   A microfluidic device for kinetic optimization of protein crystallization and in situ structure determination [J].
Hansen, CL ;
Classen, S ;
Berger, JM ;
Quake, SR .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (10) :3142-3143
[9]  
Hellman AN, 2007, ANAL CHEM, V79, P4484, DOI 10.1021/ac070081i
[10]   Pressure-driven laminar flow in tangential microchannels: an elastomeric microfluidic switch [J].
Ismagilov, RF ;
Rosmarin, D ;
Kenis, PJA ;
Chiu, DT ;
Zhang, W ;
Stone, HA ;
Whitesides, GM .
ANALYTICAL CHEMISTRY, 2001, 73 (19) :4682-4687