Role of a PH Sensitive Site in Enac Na+ Self-Inhibition

被引：0
|
作者：
Kashlan, Ossama B. [1 ]
Blobner, Brandon M. [1 ]
Zuzek, Zachary [1 ]
Tolino, Michael A. [1 ]
Kleyman, Thomas R. [1 ]
机构：
[1] Univ Pittsburgh, Pittsburgh, PA USA
来源：
BIOPHYSICAL JOURNAL | 2014年 / 106卷 / 02期
关键词：
D O I：
10.1016/j.bpj.2013.11.4139
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：752A / 752A
页数：1
相关论文
共 50 条
  • [1] Extracellular Protons Regulate Human ENaC by Modulating Na+ Self-inhibition
    Collier, Daniel M.
    Snyder, Peter M.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (02) : 792 - 798
  • [2] Functional role of extracellular loop cysteine residues of the epithelial Na+ channel in Na+ self-inhibition
    Sheng, Shaohu
    Maarouf, Ahmad B.
    Bruns, James B.
    Hughey, Rebecca P.
    Kleyman, Thomas R.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (28) : 20180 - 20190
  • [3] Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition
    Sheng, S
    Carattino, MD
    Bruns, JB
    Hughey, RP
    Kleyman, TR
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2006, 290 (06) : F1488 - F1496
  • [4] Extracellular histidine residues crucial for Na+ self-inhibition of epithelial Na+ channels
    Sheng, SH
    Bruns, JB
    Kleyman, TR
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (11) : 9743 - 9749
  • [5] A new subunit of the epithelial Na+ channel identifies regions involved in Na+ self-inhibition
    Babini, E
    Geisler, HS
    Siba, M
    Gründer, S
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (31) : 28418 - 28426
  • [6] Mutations at furin cleavage sites of ENaC subunits enhance Na plus self-inhibition
    Sheng, SH
    Carattino, MD
    Bruns, JB
    Hughey, RP
    Kleyman, TR
    FASEB JOURNAL, 2005, 19 (05): : A1174 - A1175
  • [7] Extracellular Zn2+ activates epithelial Na+ channels by eliminating Na+ self-inhibition
    Sheng, SH
    Perry, CJ
    Kleyman, TR
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (30) : 31687 - 31696
  • [8] Extracellular loop cysteine residues of gamma epithelial Na+ channel subunit and Na+ self-inhibition
    Sheng, Shaohu
    Maarouf, Ahmad B.
    Bruns, James B.
    Kleyman, Thomas R.
    FASEB JOURNAL, 2007, 21 (06): : A954 - A954
  • [9] Mutations of the conserved cysteine residues within ectodomains of epithellial Na+ channels suppress Na+ self-inhibition
    Sheng, SH
    Bruns, JB
    Kleyman, TR
    BIOPHYSICAL JOURNAL, 2005, 88 (01) : 586A - 586A
  • [10] Mutations of two histidine residues within the extracellular loops of epithelial Na+ channel subunits alter Na+ self-inhibition
    Sheng, SH
    Bruns, JB
    Kleyman, TR
    FASEB JOURNAL, 2004, 18 (05): : A1040 - A1040
12345