Biotechnological potential of plant-associated endophytic fungi:hope versus hype

被引:108
作者
Kusari, Souvik [1 ]
Singh, Satpal [2 ]
Jayabaskaran, Chelliah [2 ]
机构
[1] TU Dortmund, Chair Environm Chem & Analyt Chem, Dept Chem & Chem Biol, Inst Environm Res INFU, D-44221 Dortmund, Germany
[2] Indian Inst Sci IISc, Dept Biochem, Bangalore 560012, Karnataka, India
关键词
endophytic fungi; red biotechnology; plant-microbe interaction; endophyte biotechnology; industrial bioprocess; synthetic biology; secondary metabolites; biosynthetic pathway; SECONDARY METABOLITES; FUNGUS; PERSPECTIVE; PATHOGENS; DIVERSITY; EVOLUTION; BACTERIA;
D O I
10.1016/j.tibtech.2014.03.009
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The potential of endophytes, particularly endophytic fungi, capable of demonstrating desirable functional traits worth exploitation using red biotechnology is well established. However, these discoveries have not yet translated into industrial bioprocesses for commercial production of biopharmaceuticals using fungal endophytes. Here, we define the current challenges in transforming curiosity driven discoveries into industrial scale endophyte biotechnology. The possible practical, feasible, and sustainable strategies that can lead to harnessing fungal endophyte-mediated pharmaceutical products are discussed.
引用
收藏
页码:297 / 303
页数:7
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