Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry

被引：45
作者：
Lau, Andy M. C. [1 ]
Ahdash, Zainab [1 ]
Martens, Chloe [1 ]
Politis, Argyris [1 ]
机构：
[1] Kings Coll London, Dept Chem, London SE1 1DB, England
来源：
BIOINFORMATICS | 2019年 / 35卷 / 17期
基金：
英国惠康基金; 英国生物技术与生命科学研究理事会; 英国医学研究理事会;
关键词：
D O I：
10.1093/bioinformatics/btz022
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The Summary: Hydrogen deuterium exchange-mass spectrometry (HDX-MS) has emerged as a powerful technique for interrogating the conformational dynamics of proteins and their complexes. Currently, analysis of HDX-MS data remains a laborious procedure, mainly due to the lack of streamlined software to process the large datasets. We present Deuteros which is a standalone software designed to be coupled with Waters DynamX HDX data analysis software, allowing the rapid analysis and visualization of data from differential HDX-MS.
引用
收藏
页码：3171 / 3173
页数：3
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