Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry

被引：48

作者：

Lau, Andy M. C. ^{[1
]}

Ahdash, Zainab ^{[1
]}

Martens, Chloe ^{[1
]}

Politis, Argyris ^{[1
]}

机构：

[1] Kings Coll London, Dept Chem, London SE1 1DB, England

来源：

BIOINFORMATICS | 2019年 / 35卷 / 17期

基金：

英国惠康基金; 英国生物技术与生命科学研究理事会; 英国医学研究理事会;

关键词：

D O I：

10.1093/bioinformatics/btz022

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The Summary: Hydrogen deuterium exchange-mass spectrometry (HDX-MS) has emerged as a powerful technique for interrogating the conformational dynamics of proteins and their complexes. Currently, analysis of HDX-MS data remains a laborious procedure, mainly due to the lack of streamlined software to process the large datasets. We present Deuteros which is a standalone software designed to be coupled with Waters DynamX HDX data analysis software, allowing the rapid analysis and visualization of data from differential HDX-MS.

引用

页码：3171 / 3173

页数：3

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