Anaplastic large-cell lymphoma, T-/null-cell type

被引:47
作者
Jacobsen, Eric [1 ]
机构
[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Lymphoma Program, Boston, MA 02115 USA
关键词
anaplastic large cell lymphoma; lymphomatoid papulosis; cutaneous lymphoma; ALK;
D O I
10.1634/theoncologist.11-7-831
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Anaplastic large-cell lymphoma, T-/null-cell type (ALCL), is a rare disease that has only been well characterized for two decades. Despite this, the biology of ALCL is better understood than that of many other more common variants of lymphoma. This review focuses on the pathophysiology, clinical presentation, and therapy of ALCL, including stem cell transplantation. In particular, the text emphasizes how novel prognostic features and the evolving understanding of the biology of this disease will influence treatment selection and drug development.
引用
收藏
页码:831 / 840
页数:10
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