Concurrent treatment with Pim kinase inhibitor enhances efficacy of FLT3 inhibitors in AML with FLT3-ITD through GSK-3βactivation and GSK-3β-mediated enhanced proteasomal degradation of c-Myc and Mcl-1

被引:0
作者
Lee, Jonelle [1 ]
Scarpa, Mario [2 ]
Chatterjee, Aditi [2 ]
Ali, Mooath Mustafa [2 ]
Singh, Prerna [2 ]
Kapoor, Shivani [2 ]
Trotta, Rossana [1 ]
Baer, Maria [2 ]
机构
[1] Univ Maryland, Baltimore, MD 21201 USA
[2] Univ Maryland, Greenebaum Comprehens Canc Ctr, Baltimore, MD 21201 USA
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3338
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页数:2
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