Understanding of immunologic mechanisms involved in the initiation and perpetuation of chronic inflammation has led to new therapeutic opportunities in the inflammatory bowel diseases. The term "biologics" is used to distinguish new biotechnologic therapeutics from the conventional drugs used in the treatment of immune-mediated inflammatory disorders. This article reviews novel biologic therapies that are being investigated for the treatment of Crohn's disease and ulcerative colitis.
机构:
Henry D Janowitz Div Gastroenterol, One Gustave L Levy Pl, New York, NY USAHenry D Janowitz Div Gastroenterol, One Gustave L Levy Pl, New York, NY USA
Borman, Zachary A.
Cote-Daigneault, Justin
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CHUM, Gastroenterol Serv, Montreal, PQ, CanadaHenry D Janowitz Div Gastroenterol, One Gustave L Levy Pl, New York, NY USA
Cote-Daigneault, Justin
Colombel, Jean-Frederic
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Henry D Janowitz Div Gastroenterol, One Gustave L Levy Pl, New York, NY USAHenry D Janowitz Div Gastroenterol, One Gustave L Levy Pl, New York, NY USA
机构:
Univ Sao Paulo, Dept Gastroenterol, Sch Med, Dr Eneas Carvalho Aguiar 255, BR-05403000 Sao Paulo, BrazilUniv Sao Paulo, Dept Gastroenterol, Sch Med, Dr Eneas Carvalho Aguiar 255, BR-05403000 Sao Paulo, Brazil
Queiroz, Natalia S. F.
Regueiro, Miguel
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Pier C & Renee A Borra Family Endowed Chair Gastr, Dept Gastroenterol Hepatol & Nutr, Cleveland, OH USAUniv Sao Paulo, Dept Gastroenterol, Sch Med, Dr Eneas Carvalho Aguiar 255, BR-05403000 Sao Paulo, Brazil
机构:
Beth Israel Deaconess Med Ctr, Ctr Inflammatory Bowel Dis, Div Gastroenterol, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Ctr Inflammatory Bowel Dis, Div Gastroenterol, Boston, MA 02215 USA
Deyhim, Tina
Cheifetz, Adam S.
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Beth Israel Deaconess Med Ctr, Ctr Inflammatory Bowel Dis, Div Gastroenterol, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Ctr Inflammatory Bowel Dis, Div Gastroenterol, Boston, MA 02215 USA
Cheifetz, Adam S.
Papamichael, Konstantinos
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Beth Israel Deaconess Med Ctr, Ctr Inflammatory Bowel Dis, Div Gastroenterol, Boston, MA 02215 USABeth Israel Deaconess Med Ctr, Ctr Inflammatory Bowel Dis, Div Gastroenterol, Boston, MA 02215 USA