Citrus fruits as a treasure trove of active natural metabolites that potentially provide benefits for human health

被引：219

作者：

Lv, Xinmiao ^{[1
]}

Zhao, Siyu ^{[1
]}

Ning, Zhangchi ^{[1
]}

Zeng, Honglian ^{[1
]}

Shu, Yisong ^{[1
]}

Tao, Ou ^{[1
]}

Xiao, Cheng ^{[2
]}

Lu, Cheng ^{[3
,4
]}

Liu, Yuanyan ^{[1
]}

机构：

[1] Beijing Univ Chinese Med, Sch Chinese Mat Med, Beijing 100029, Peoples R China

[2] China Japan Friendship Hosp, Inst Clin Med, Beijing 100029, Peoples R China

[3] China Acad Chinese Med Sci, Inst Basic Res Clin Med, Beijing 100700, Peoples R China

[4] Hong Kong Baptist Univ, Sch Chinese Med, Kowloon Tong 999077, Hong Kong, Peoples R China

来源：

CHEMISTRY CENTRAL JOURNAL | 2015年 / 9卷

基金：

美国国家科学基金会; 北京市自然科学基金;

关键词：

Citrus fruits; Secondary metabolites; Bioactivities; Human health; Flavonoids; CEREBRAL GLOBAL-ISCHEMIA; NITRIC-OXIDE SYNTHASE; ANTIINFLAMMATORY PROPERTIES; FLAVANONE GLYCOSIDES; ANTIOXIDANT ACTIVITY; INHIBITORY-ACTIVITY; BETA-CRYPTOXANTHIN; BERGAMIA RISSO; ESSENTIAL OILS; CV SUAVISSIMA;

D O I：

10.1186/s13065-015-0145-9

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Citrus fruits, which are cultivated worldwide, have been recognized as some of the most high-consumption fruits in terms of energy, nutrients and health supplements. What is more, a number of these fruits have been used as traditional medicinal herbs to cure diseases in several Asian countries. Numerous studies have focused on Citrus secondary metabolites as well as bioactivities and have been intended to develop new chemotherapeutic or complementary medicine in recent decades. Citrus-derived secondary metabolites, including flavonoids, alkaloids, limonoids, coumarins, carotenoids, phenolic acids and essential oils, are of vital importance to human health due to their active properties. These characteristics include anti-oxidative, anti-inflammatory, anti-cancer, as well as cardiovascular protective effects, neuroprotective effects, etc. This review summarizes the global distribution and taxonomy, numerous secondary metabolites and bioactivities of Citrus fruits to provide a reference for further study. Flavonoids as characteristic bioactive metabolites in Citrus fruits are mainly introduced.

引用

页数：14