Dispersive solid-phase imprinting of proteins for the production of plastic antibodies

被引：22

作者：

Ashley, Jon ^{[1
]}

Feng, Xiaotong ^{[1
]}

Halder, Arnab ^{[1
]}

Zhou, Tongchang ^{[1
]}

Sun, Yi ^{[1
]}

机构：

[1] Tech Univ Denmark, Dept Micro & Nanotechnol, DK-2800 Lyngby, Denmark

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 27期

关键词：

POLYMER NANOPARTICLES; RECOGNITION; AFFINITY;

D O I：

10.1039/c8cc00343b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe a novel dispersive solid-phase imprinting technique for the production of nano-sized molecularly imprinted polymers (nanoMIPs) as plastic antibodies. The template was immobilized on in-house synthesized magnetic microspheres instead of conventional glass beads. As a result, high-affinity and template-free MIPs were produced in higher yields.

引用

页码：3355 / 3358

页数：4

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