botulinum toxin A;
multipoint and multilevel injection technique;
Facial Line Treatment Satisfaction Questionnaire;
INTERNATIONAL CONSENSUS RECOMMENDATIONS;
GLABELLAR LINES;
SPEYWOOD UNIT;
DOUBLE-BLIND;
EFFICACY;
SAFETY;
FACE;
WRINKLES;
USAGE;
D O I:
10.1111/jocd.12090
中图分类号:
R75 [皮肤病学与性病学];
学科分类号:
100206 ;
摘要:
Botulinum toxin represents one of the most frequently requested cosmetic procedures. We treated 223 patients with facial wrinkles using a new technique of injection of botulinum toxin A (BTA) called multipoint and multilevel injection technique (MMIT). The aim of MMIT was to relax the muscle and not paralyze it. Patient satisfaction was evaluated by Facial Line Treatment Satisfaction Questionnaire (FTSQ). Treatment with botulinum toxin determined a good response in all patients. Facial rhytids were completely resolved in case of young skin and well reduced in case of aged skin, leaving a natural aspect both in static and dynamic wrinkles. Patient mean overall satisfaction evaluated with FTSQ was 6.4 +/- 1.1. In our experience, the use of botulin toxin by MMIT consents a better calibration of action with a soft and natural result. This can be achieved by distributing the BTA dose through various injection points for each area (multipoint injections). Furthermore, injections can be performed at different levels (multilevel injections). The level of injections regulates the potency of effect on the muscle: if the level is deep (intramuscular), the effect will be strong while if it is medium or superficial (subcutaneous and intradermal), the effect will be soft. This consents a fine calibration of action on muscle activity with a personal aesthetic result.
机构:
Univ Porto, Fac Dent Med, R Dr Manuel Pereira da Silva, P-4200393 Porto, PortugalUniv Porto, Fac Dent Med, R Dr Manuel Pereira da Silva, P-4200393 Porto, Portugal
Pereira, Ines Novo
Hassan, Haidar
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机构:
Queen Mary Univ, Blizard Inst Cell & Mol Sci, Ctr Cutaneous Res, Barts & London Sch Med & Dent, 4 Newark St, London E1 2AT, EnglandUniv Porto, Fac Dent Med, R Dr Manuel Pereira da Silva, P-4200393 Porto, Portugal
机构:
Southern Med Univ, Nan Fang Hosp, Dept Plast & Aesthet Surg, 1838 North Guangzhou AV, Guangzhou, Guangdong, Peoples R ChinaSouthern Med Univ, Nan Fang Hosp, Dept Plast & Aesthet Surg, 1838 North Guangzhou AV, Guangzhou, Guangdong, Peoples R China
Cheng, Shaoping
Miao, Yong
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机构:
Southern Med Univ, Nan Fang Hosp, Dept Plast & Aesthet Surg, 1838 North Guangzhou AV, Guangzhou, Guangdong, Peoples R ChinaSouthern Med Univ, Nan Fang Hosp, Dept Plast & Aesthet Surg, 1838 North Guangzhou AV, Guangzhou, Guangdong, Peoples R China
Miao, Yong
Hu, Zhiqi
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机构:
Southern Med Univ, Nan Fang Hosp, Dept Plast & Aesthet Surg, 1838 North Guangzhou AV, Guangzhou, Guangdong, Peoples R ChinaSouthern Med Univ, Nan Fang Hosp, Dept Plast & Aesthet Surg, 1838 North Guangzhou AV, Guangzhou, Guangdong, Peoples R China
机构:
Univ Toronto, Temerty Fac Med, Div Dermatol, Toronto, ON, Canada
1093 Rue Reynald, Laval, PQ, CanadaUniv Toronto, Temerty Fac Med, Div Dermatol, Toronto, ON, Canada
Hanna, Edith
Xing, Lin
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机构:
Univ Toronto, Temerty Fac Med, Div Dermatol, Toronto, ON, CanadaUniv Toronto, Temerty Fac Med, Div Dermatol, Toronto, ON, Canada
Xing, Lin
Taylor, Jennifer H.
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机构:
Univ Toronto, Temerty Fac Med, Div Dermatol, Toronto, ON, CanadaUniv Toronto, Temerty Fac Med, Div Dermatol, Toronto, ON, Canada
Taylor, Jennifer H.
Bertucci, Vince
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机构:
Univ Toronto, Temerty Fac Med, Div Dermatol, Toronto, ON, CanadaUniv Toronto, Temerty Fac Med, Div Dermatol, Toronto, ON, Canada