What influences preneoplastic colorectal lesion recurrence?

被引：8
作者：
De Maio, Giulia [1 ]
Zama, Elisa [1 ]
Rengucci, Claudia [1 ]
Calistri, Daniele [1 ]
机构：
[1] Ist Sci Romagnolo Studio & Cura Tumori IRST, IRCCS, Biosci Lab, Meldola, FC, Italy
来源：
ONCOTARGET | 2017年 / 8卷 / 07期
关键词：
recurrence; preneoplastic lesions; suppressor and serrated pathway; microbiota; TRADITIONAL SERRATED ADENOMA; HYPERPLASTIC POLYPS; PROMOTER METHYLATION; RISK; PATHWAY; CANCER; NEOPLASIA; COLONOSCOPY; MICROBIOME; EXPRESSION;
D O I：
10.18632/oncotarget.13628
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The hypothesis of the local recurrence of preneoplastic lesions was first put forward in the 1950s. Disease recurrence may result from an inherent imbalance in cell proliferation that promotes carcinogenesis in apparently normal mucosa. Our review sheds light on how early preneoplastic lesions could be used to diagnose relapsed preneoplastic and, developing neoplastic lesions. We focus in detail on the clinical-pathological and molecular features of adenoma subtypes and their role in relapsed adenoma and their development into colorectal carcinoma. Moreover, we include the data available on microbiota and its metabolites and their role in recurrence. We strongly believe that a significant improvement could be achieved in colorectal screening by introducing personalized endoscopic surveillance for polyp-bearing patients on the basis of the presence of molecular markers that are predictive of recurrence.
引用
收藏
页码：12406 / 12416
页数：11
相关论文
共 95 条
  • [11] Gut Microbiome and Colorectal Adenomas[J]. Dulal, Santosh;Keku, Temitope O. CANCER JOURNAL, 2014(03)
  • [12] The serrated polyp: getting it right![J]. Ensari, A.;Bosman, F. T.;Offerhaus, G. J. A. JOURNAL OF CLINICAL PATHOLOGY, 2010(08)
  • [13] Colorectal cancers found after a complete colonoscopy[J]. Farrar, William D.;Sawhney, Mandeep S.;Nelson, Douglas B.;Lederle, Frank A.;Bond, John H. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2006(10)
  • [14] PDCD4 nuclear loss inversely correlates with miR-21 levels in colon carcinogenesis[J]. Fassan, Matteo;Pizzi, Marco;Giacomelli, Luciano;Mescoli, Claudia;Ludwig, Kathrin;Pucciarelli, Salvatore;Rugge, Massimo. VIRCHOWS ARCHIV, 2011(04)
  • [15] Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012[J]. Ferlay, Jacques;Soerjomataram, Isabelle;Dikshit, Rajesh;Eser, Sultan;Mathers, Colin;Rebelo, Marise;Parkin, Donald Maxwell;Forman, David;Bray, Freddie. INTERNATIONAL JOURNAL OF CANCER, 2015(05)
  • [16] The CIMP Phenotype in BRAF Mutant Serrated Polyps from a Prospective Colonoscopy Patient Cohort[J]. Fernando, Winnie C.;Miranda, Mariska S.;Worthley, Daniel L.;Togashi, Kazutomo;Watters, Dianne J.;Leggett, Barbara A.;Spring, Kevin J. GASTROENTEROLOGY RESEARCH AND PRACTICE, 2014
  • [17] Tumour-associated and non-tumour-associated microbiota in colorectal cancer[J]. Flemer, Burkhardt;Lynch, Denise B.;Brown, Jillian M. R.;Jeffery, Ian B.;Ryan, Feargal J.;Claesson, Marcus J.;O'Riordain, Micheal;Shanahan, Fergus;O'Toole, Paul W. GUT, 2017(04)
  • [18] Fu XS, 2014, ANAL QUANT CYTOPATHO, V36, P351
  • [19] A multinational, Internet-based assessment of observer variability in the diagnosis of serrated colorectal polyps[J]. Glatz, Katharina;Pritt, Bobbi;Glatz, Dieter;Hartmann, Arndt;O'Brien, Michael J.;Blaszyk, Hagen. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2007(06)
  • [20] Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline[J]. Hassan, Cesare;Quintero, Enrique;Dumonceau, Jean-Marc;Regula, Jaroslaw;Brandao, Catarina;Chaussade, Stanislas;Dekker, Evelien;Dinis-Ribeiro, Mario;Ferlitsch, Monika;Gimeno-Garcia, Antonio;Hazewinkel, Yark;Jover, Rodrigo;Kalager, Mette;Loberg, Magnus;Pox, Christian;Rembacken, Bjorn;Lieberman, David. ENDOSCOPY, 2013(10)
12345678910