Functionalization of [60]Fullerene via Palladium-Catalyzed C-H Bond Activation

The palladium-catalyzed C-H bond activation strategy has been successfully applied to fullerene chemistry, and several types of [60] fullerene-fused heterocycles and carbocycles have been obtained. The synthesis of [60] fullerene-fused indolines, isoquinolinones, azepines, tetrahydroisoquinolines, tetrahydrobenzazepines, sultones, tetrahydrobenzooxepines/isochromans, and dihydrophenanthrenes has been achieved by the palladium-catalyzed reactions of [60] fullerene with anilides, benzamides, N-sulfonyl-2-aminobiaryls, N-benzyl sulfonamides, N-(2-arylethyl) sulfonamides, arylsulfonic acids, 2-phenylethyl/benzyl alcohols, and 2-arylbenzoic acids, respectively.