Combining insoluble and soluble factors to steer stem cell fate

被引：70

作者：

Dave, P. C. ^{[1
]}

Dingal, P. ^{[1
]}

Discher, Dennis E. ^{[1
,2
,3
]}

机构：

[1] Biophys Engn Lab Chem & Biomol Engn, Philadelphia, PA 19104 USA

[2] Univ Penn, Phys Grp, Philadelphia, PA 19104 USA

[3] Univ Penn, Cell & Mol Biol Grad Grp, Philadelphia, PA 19104 USA

来源：

NATURE MATERIALS | 2014年 / 13卷 / 06期

关键词：

BONE-MARROW NICHE; HEMATOPOIETIC STEM; SELF-RENEWAL; PROGENITOR CELLS; IN-VIVO; DIFFERENTIATION; MUSCLE; CULTURE; MATRIX; EXPANSION;

D O I：

10.1038/nmat3997

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Materials-based control of stem cell fate is beginning to be rigorously combined with traditional soluble-factor approaches to better understand the cells' behaviour and maximize their potential for therapy.

引用

页码：532 / 537

页数：6

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