Mechanic Forces Promote Brain Endothelial Activation by SARS-CoV-2 Spike Protein

被引:0
作者
Babendreyer, Aaron [1 ]
Ludwig, Andreas [1 ]
机构
[1] Rhein Westfal TH Aachen, Inst Mol Pharmacol, Pauwelsstr 30, D-52074 Aachen, Germany
关键词
Editorials; brain; endothelial cells; extracellular matrix; inflammation; SARS-COV; ACE2; CORONAVIRUS; RECEPTOR;
D O I
10.1161/STROKEAHA.120.033119
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:271 / 273
页数:3
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  • [1] The metalloproteinase ADAM15 is upregulated by shear stress and promotes survival of endothelial cells
    Babendreyer, Aaron
    Molls, Lisa
    Simons, Indra M.
    Dreymueller, Daniela
    Biller, Kristina
    Jahr, Holger
    Denecke, Bernd
    Boon, Reinier A.
    Bette, Sebastian
    Schnakenberg, Uwe
    Ludwig, Andreas
    [J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2019, 134 : 51 - 61
  • [2] Shear Stress Counteracts Endothelial CX3CL1 Induction and Monocytic Cell Adhesion
    Babendreyer, Aaron
    Molls, Lisa
    Dreymueller, Daniela
    Uhlig, Stefan
    Ludwig, Andreas
    [J]. MEDIATORS OF INFLAMMATION, 2017, 2017
  • [3] Key transcriptional regulators of the vasoprotective effects of shear stress
    Boon, R. A.
    Horrevoets, A. J. G.
    [J]. HAMOSTASEOLOGIE, 2009, 29 (01): : 39 - +
  • [4] Status update on iRhom and ADAM17: It's still complicated
    Duesterhoeft, Stefan
    Babendreyer, Aaron
    Giese, Anja Adelina
    Flasshove, Charlotte
    Ludwig, Andreas
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2019, 1866 (10): : 1567 - 1583
  • [5] COVID-19 related stroke in young individuals
    Fifi, Johanna T.
    Mocco, J.
    [J]. LANCET NEUROLOGY, 2020, 19 (09) : 713 - 715
  • [6] Modulation of TNF-α-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-α production and facilitates viral entry
    Haga, Shiori
    Yamamoto, Norio
    Nakai-Murakami, Chikako
    Osawa, Yoshiaki
    Tokunaga, Kenzo
    Sata, Tetsutaro
    Yamamoto, Naoki
    Sasazuki, Takehiko
    Ishizaka, Yukihito
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (22) : 7809 - 7814
  • [7] Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis
    Hamming, I
    Timens, W
    Bulthuis, MLC
    Lely, AT
    Navis, GJ
    van Goor, H
    [J]. JOURNAL OF PATHOLOGY, 2004, 203 (02) : 631 - 637
  • [8] SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
    Hoffmann, Markus
    Kleine-Weber, Hannah
    Schroeder, Simon
    Krueger, Nadine
    Herrler, Tanja
    Erichsen, Sandra
    Schiergens, Tobias S.
    Herrler, Georg
    Wu, Nai-Huei
    Nitsche, Andreas
    Mueller, Marcel A.
    Drosten, Christian
    Poehlmann, Stefan
    [J]. CELL, 2020, 181 (02) : 271 - +
  • [9] Expression and regulation of the neutral amino acid transporter B0AT1 in rat small intestine
    Jando, Julia
    Camargo, Simone M. R.
    Herzog, Brigitte
    Verrey, Francois
    [J]. PLOS ONE, 2017, 12 (09):
  • [10] Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection
    Kaneko, Naoki
    Satta, Sandro
    Komuro, Yutaro
    Muthukrishnan, Sree Deepthi
    Kakarla, Visesha
    Guo, Lea
    An, Jennifer
    Elahi, Fanny
    Kornblum, Harley, I
    Liebeskind, David S.
    Hsiai, Tzung
    Hinman, Jason D.
    [J]. STROKE, 2021, 52 (01) : 260 - 270