Duration but not intensity influences transcranial direct current stimulation (tDCS) after-effects on cortical excitability

被引:40
|
作者
Vignaud, Philippe [1 ,2 ,4 ]
Mondino, Marine [1 ,2 ]
Poulet, Emmanuel [1 ,3 ]
Palm, Ulrich [4 ]
Brunelin, Jerome [1 ,2 ]
机构
[1] Univ Claude Bernard Lyon 1, Team PSYR2, Lyon Neurosci Res Ctr, Inserm U1028,CNRS UMR5292, F-69000 Lyon, France
[2] Ctr Hosp Le Vinatier, F-69677 Bron, France
[3] Hop Edouard Herriot, Dept Psychiat Emergency, F-69008 Lyon, France
[4] Ludwig Maximilians Univ Munchen, Munich Ctr Brain Stimulat, Dept Psychiat & Psychotherapy, Nussbaumstr 7, D-80336 Munich, Germany
来源
关键词
Facilitation; Inhibition motor cortex; Neuromodulation; Stimulation parameters; INTERVAL INTRACORTICAL INHIBITION; MOTOR CORTEX EXCITABILITY; VARIABILITY; HUMANS; SESSIONS;
D O I
10.1016/j.neucli.2018.02.001
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Recent studies have shown heterogeneous results regarding the influence of intensity and duration of motor transcranial direct current stimulation (tDCS) on cortical excitability. In this pilot crossover study including 14 healthy participants, we compared the effects of a single session of anodal-tDCS set with two commonly used durations (20 and 30 minutes) and intensities (1 and 2 mA) on short-interval intracortical inhibition (SICI) and intracortical facilitation (ICE). Regardless of the current intensity, 20 minutes of tDCS increased SICI (3 ms inter-stimulus interval ISI) and decreased ICF (7 ms ISI); 30 minutes of tDCS did not affect cortical excitability. (C) 2018 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:89 / 92
页数:4
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