Development of a suspension copolymerization process for bone cement production

被引:0
作者
Cordoví, CM
De Lucas, A
Durán, A
Rodríguez, JF
机构
[1] Univ Castilla La Mancha, Fac Chem, Dept Chem Engn, Ciudad Real 13004, Spain
[2] ISPJAE, Fac Chem Engn, Res Ctr Proc Engn, La Habana, Cuba
关键词
methyl methacrylate; styrene; suspension; polymerization; scale up; Rushton stirrer; simulation;
D O I
10.1002/(SICI)1097-4628(20000509)76:6<814::AID-APP7>3.0.CO;2-5
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Copolymers of MMA-STY with the suitable composition, particle size distribution, and molecular weight distribution for its medical application as bone cements have been obtained by means of suspension copolymerization. The influence of the stirring rate on the final mean particle size has been established, and the scale-up of the process has been performed with successful results. The application of a kinetic model allowed to estimate the copolymer composition during the process, which is essential to obtain polymers with adequate properties. (C) 2000 John Wiley & Sons, Inc.
引用
收藏
页码:814 / 823
页数:10
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