Understanding the Colloidal Stability of the Mesoporous MIL-100(Fe) Nanoparticles in Physiological Media

被引：128
作者：
Bellido, Elena [1 ]
Guillevic, Mazheva [1 ]
Hidalgo, Tania [1 ]
Santander-Ortega, Manuel J. [2 ]
Serre, Christian [1 ]
Horcajada, Patricia [1 ]
机构：
[1] Univ Versailles St Quentin En Yvelines, UMR CNRS 8180, Inst Lavoisier Versailles, F-78035 Versailles, France
[2] Univ Santiago de Compostela, Nanobiofar Ctr Mol Med & Chron Dis CIMUS, Santiago De Compostela 15706, Spain
来源：
LANGMUIR | 2014年 / 30卷 / 20期
关键词：
METAL-ORGANIC FRAMEWORKS; BOVINE SERUM-ALBUMIN; DRUG-DELIVERY; PARTICLES; MOLECULES; POLOXAMER; SYSTEMS; PLGA;
D O I：
10.1021/la5012555
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The colloidal and chemical stability of nanoparticles of the nontoxic and biodegradable iron(III) trimesate MIL-100(Fe) nanocarrier have been evaluated in the presence of a series of simulated physiological fluids for intravenous and oral administration. MIL-100(Fe) nanoparticles exhibit an appropriate colloidal stability and biodegradability, mainly dependent on both the nature of their physicochemical surface and the media composition, being a priori compatible with their biomedical use.
引用
收藏
页码：5911 / 5920
页数：10
相关论文
共 40 条
  • [1] Towards an Improved anti-HIV Activity of NRTI via Metal-Organic Frameworks Nanoparticles
    Agostoni, Valentina
    Chalati, Tamim
    Horcajada, Patricia
    Willaime, Herve
    Anand, Resmi
    Semiramoth, Nicolas
    Baati, Tarek
    Hall, Shaun
    Maurin, Guillaume
    Chacun, Helene
    Bouchemal, Kawthar
    Martineau, Charlotte
    Taulelle, Francis
    Couvreur, Patrick
    Rogez-Kreuz, Christine
    Clayette, Pascal
    Monti, Sandra
    Serre, Christian
    Gref, Ruxandra
    [J]. ADVANCED HEALTHCARE MATERIALS, 2013, 2 (12) : 1630 - 1637
  • [2] 'Green' fluorine-free mesoporous iron(III) trimesate nanoparticles for drug delivery
    Agostoni, Valentina
    Horcajada, Patricia
    Rodriguez-Ruiz, Violeta
    Willaime, Herve
    Couvreur, Patrick
    Serre, Christian
    Gref, Ruxandra
    [J]. GREEN MATERIALS, 2013, 1 (04) : 209 - 217
  • [3] [Anonymous], 2010, European Pharmacopeia (EP)
  • [4] In depth analysis of the in vivo toxicity of nanoparticles of porous iron(III) metal-organic frameworks
    Baati, Tarek
    Njim, Leila
    Neffati, Fadoua
    Kerkeni, Abdelhamid
    Bouttemi, Muriel
    Gref, Ruxandra
    Najjar, Mohamed Fadhel
    Zakhama, Abdelfateh
    Couvreur, Patrick
    Serre, Christian
    Horcajada, Patricia
    [J]. CHEMICAL SCIENCE, 2013, 4 (04) : 1597 - 1607
  • [5] Time Evolution of the Nanoparticle Protein Corona
    Casals, Eudald
    Pfaller, Tobias
    Duschl, Albert
    Oostingh, Gertie Janneke
    Puntes, Victor
    [J]. ACS NANO, 2010, 4 (07) : 3623 - 3632
  • [6] Detailed identification of plasma proteins adsorbed on copolymer nanoparticles
    Cedervall, Tommy
    Lynch, Iseult
    Foy, Martina
    Berggard, Tord
    Donnelly, Seamas C.
    Cagney, Gerard
    Linse, Sara
    Dawson, Kenneth A.
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (30) : 5754 - 5756
  • [7] Rationalization of the entrapping of bioactive molecules into a series of functionalized porous zirconium terephthalate MOFs
    Cunha, D.
    Gaudin, C.
    Colinet, I.
    Horcajada, P.
    Maurin, G.
    Serre, C.
    [J]. JOURNAL OF MATERIALS CHEMISTRY B, 2013, 1 (08) : 1101 - 1108
  • [8] Nanoscale Metal-Organic Frameworks for Biomedical Imaging and Drug Delivery
    Della Rocca, Joseph
    Liu, Demin
    Lin, Wenbin
    [J]. ACCOUNTS OF CHEMICAL RESEARCH, 2011, 44 (10) : 957 - 968
  • [9] About the Stability and Charging of the Aerosols
    Fuchs, N.
    [J]. ZEITSCHRIFT FUR PHYSIK, 1934, 89 (11-12): : 736 - 743
  • [10] Garcia-Marquez A., 2012, EUR J INORG CHEM, P5165
1234