Eltgol Acutelly Improves Airway Clearance and Reduces Static Pulmonary Volumes in Adult Cystic Fibrosis Patients
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作者:
Guimaraes, Fernando Silva
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Augusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, Brazil
Univ Fed Rio de Janeiro, Phys Therapy Dept, BR-21941 Rio De Janeiro, BrazilAugusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, Brazil
Guimaraes, Fernando Silva
[1
,2
]
Lopes, Agnaldo Jose
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Univ Estado Rio De Janeiro, Physiol Resp Lab, Rio De Janeiro, BrazilAugusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, Brazil
Lopes, Agnaldo Jose
[3
]
Ribeiro Moco, Vanessa Joaquim
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Augusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, BrazilAugusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, Brazil
Ribeiro Moco, Vanessa Joaquim
[1
]
de Souza, Felipe Cavalcanti
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Augusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, BrazilAugusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, Brazil
de Souza, Felipe Cavalcanti
[1
]
Silveira de Menezes, Sara Lucia
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Augusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, Brazil
Univ Fed Rio de Janeiro, Phys Therapy Dept, BR-21941 Rio De Janeiro, BrazilAugusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, Brazil
Silveira de Menezes, Sara Lucia
[1
,2
]
机构:
[1] Augusto Motta Univ Ctr UNISUAM, Rehabil Sci Grad Program, BR-21041021 Rio De Janeiro, Brazil
[2] Univ Fed Rio de Janeiro, Phys Therapy Dept, BR-21941 Rio De Janeiro, Brazil
[3] Univ Estado Rio De Janeiro, Physiol Resp Lab, Rio De Janeiro, Brazil
[Purpose] Chest physical therapy techniques are essential in order to reduce the frequency of recurrent pulmonary infections that progressively affect lung function in cystic fibrosis patients. Recently, ELTGOL (L'Expiration Lente Totale Glotte Ouverte en d cubitus Lat ral) emerged as an inexpensive and easy to perform therapeutic option. The aim of this study was to compare the acute effects of ELTGOL and the Flutter valve in stable adult patients with cystic fibrosis. [Subjects and Methods] This was a randomized, crossover study with a sample of cystic fibrosis outpatients. The subjects underwent two protocols (Flutter Valve and ELTGOL interventions, referred to as ELTGOL and FLUTTER) in a randomized order with a one-week washout interval between them. The main outcomes were pulmonary function variables and expectorated sputum dry weight. [Results] ELTGOL cleared 0.34 g more of secretions than FLUTTER (95% CI 0.11 to 0.57). When comparing the physiological effects of ELTGOL and FLUTTER, the first was superior in improving airway resistance (-0.51 cmH2O/L/s; 95% CI -0.88 to -0.14) and airway conductance (0.016 L/s/cmH2O; 95% CI 0.008 to 0.023). [Conclusion] ELTGOL promoted higher secretion removal and improvement in airway resistance and conductance than the Flutter valve. These techniques were equivalent in reducing the pulmonary hyperinflation and air trapping in cystic fibrosis patients.
机构:
Prince Charles Hosp, Adult Cyst Fibrosis Ctr, Brisbane, Qld, AustraliaPrince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
Moore, Vanessa
MacMorran, Kate
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Prince Charles Hosp, Adult Cyst Fibrosis Ctr, Brisbane, Qld, Australia
Prince Charles Hosp, Psychol Dept, Brisbane, Qld, AustraliaPrince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
MacMorran, Kate
Castellini, Julieta
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Prince Charles Hosp, Adult Cyst Fibrosis Ctr, Brisbane, Qld, Australia
Prince Charles Hosp, Psychol Dept, Brisbane, Qld, AustraliaPrince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
Castellini, Julieta
Hay, Karen
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QIMR Berghofer Med Res Inst, Brisbane, Qld, AustraliaPrince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
Hay, Karen
Keegan, Vernon
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Prince Charles Hosp, Adult Cyst Fibrosis Ctr, Brisbane, Qld, Australia
Prince Charles Hosp, Social Work Dept, Brisbane, Qld, AustraliaPrince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
Keegan, Vernon
Reid, David
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机构:
Prince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
Univ Queensland, Brisbane, Qld 4072, Australia
James Cook Univ, Townsville, Qld, AustraliaPrince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
Reid, David
Curtin, Deanne
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Prince Charles Hosp, Dept Thorac Med, Brisbane, Qld, AustraliaPrince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
Curtin, Deanne
Tay, George
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机构:
Prince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
Univ Queensland, Brisbane, Qld 4072, Australia
QIMR Berghofer Med Res Inst, Brisbane, Qld, AustraliaPrince Charles Hosp, Dept Thorac Med, Brisbane, Qld, Australia
机构:
St James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, EnglandSt James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, England
Etherington, C.
Naseer, R.
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St James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, EnglandSt James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, England
Naseer, R.
Conway, S. P.
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St James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, EnglandSt James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, England
Conway, S. P.
Whitaker, P.
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St James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, EnglandSt James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, England
Whitaker, P.
Denton, M.
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Leeds Gen Infirm, Dept Microbiol, Leeds LS1 3BR, W Yorkshire, EnglandSt James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, England
Denton, M.
Peckham, D. G.
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St James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, EnglandSt James Univ Hosp, Reg Adult Cyst Fibrosis Unit, Leeds LS9 7TF, W Yorkshire, England
机构:
CHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Univ Paris Est Creteil UPEC, Ecole Natl Vet Alfort ENVA, Fac Sante, UR Dynamyc 7380, Creteil, France
USC Anses, Maisons Alfort, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Angebault, Cecile
Vandenborght, Louise-Eva
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Genoscreen, Lille, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Vandenborght, Louise-Eva
Bassinet, Laurence
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Ctr Hospitalier Intercommunal Creteil, Serv Pneumol, Creteil, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Bassinet, Laurence
Wizla, Nathalie
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CHU Lille, Serv Gastro Enterol Hepatol Pediat, Lille, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Wizla, Nathalie
Ferroni, Agnes
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CHU Necker Enfants Malad, APHP, Serv Microbiol Clin, Paris, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Ferroni, Agnes
Dessein, Rodrigue
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CHU Lille, Serv Bacteriol, Lille, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Dessein, Rodrigue
Remus, Natacha
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Ctr Hospitalier Intercommunal Creteil, Serv Pediat Gen, Creteil, France
Ctr Malad Resp Rares, Respirare, CRCM, Creteil, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Remus, Natacha
Thumerelle, Caroline
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CHU Lille, Serv Pediat, Lille, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Thumerelle, Caroline
Fauchet, Nathalie
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Ctr Hospitalier Intercommunal Creteil, Serv Microbiol, Creteil, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Fauchet, Nathalie
Epaud, Ralph
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机构:
Ctr Hospitalier Intercommunal Creteil, Serv Pediat Gen, Creteil, France
Ctr Malad Resp Rares, Respirare, CRCM, Creteil, France
Univ Paris Est Creteil, INSERM, IMRB, Creteil, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France
Epaud, Ralph
Delhaes, Laurence
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CHU Bordeaux, Grp Hospitalier Pellegrin, Serv Parasitol Mycol, Bordeaux, France
Univ Bordeaux, INSERM, U1045, Bordeaux, FranceCHU Henri Mondor, AP HP, Unite Parasitol Mycol, Dept Prevent Diagnost & Traitement Infect, Creteil, France