First Reported Case of Infective Endocarditis Caused by Community-Acquired Methicillin-Resistant Staphylococcus aureus Not Associated With Healthcare Contact in Brazil

被引：16

作者：

Fortes, Claudio Querido ^{[1
]}

Espanha, Claudia Adelino ^{[1
]}

Bustorff, Flavio Pedreira ^{[1
]}

Zappa, Bruno Cordeiro ^{[1
]}

Pires Ferreira, Adriana Lucia ^{[1
]}

Moreira, Regina Barbosa ^{[1
]}

Pereira, Nelson Goncalves ^{[1
]}

Fowler, Vance G., Jr. ^{[2
]}

Deshmukh, Hitesh ^{[2
]}

机构：

[1] Clementino Fraga Filho Hosp, Rio De Janeiro, Brazil

[2] Duke Univ, Med Ctr, Durham, NC USA

来源：

BRAZILIAN JOURNAL OF INFECTIOUS DISEASES | 2008年 / 12卷 / 06期

关键词：

Infective endocarditis; CA-MRSA; Brazil; PVL;

D O I：

10.1590/S1413-86702008000600020

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report here the first case of endocarditis due to CA-MRSA not associated with healthcare contact in Brazil in Brazil. A previously healthy patient presented with history of endocarditis following a traumatic wound infection. Patient had multiple positive blood cultures within 72 h of admission and met modified Duke's criterion for infective endocarditis. The isolate was typed as Staphylococcal cassette chromosome (SCC) mec type IV and was positive for presence of Panton-Valentine leukocidin (PVL). Increased incidence of CA-MRSA endocarditis is a challenge for the internist to choose the best empirical therapy. Several authors have suggested an empirical therapy with both a beta-lactam and an anti-MRSA agent for serious S. aureus infections. Our patient was treated with Vancomycin and made complete recovery in 3 months.

引用

页码：541 / 543

页数：3

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