The comparative studies of charge storage stabilities among three PP/porous PTFE/PP electret

被引:21
作者
Cui, L. L. [2 ]
Song, M. H. [1 ]
Kong, Y. X. [2 ]
Cheng, L. [1 ]
Wang, D. [2 ]
Xiao, Y. H. [2 ]
Jiang, J. [1 ]
机构
[1] Second Mil Med Univ, Fac Basic Med Sci, Dept Math & Phys, Shanghai 200433, Peoples R China
[2] Second Mil Med Univ, Sch Pharm, Dept Inorgan Chem, Shanghai 200433, Peoples R China
基金
中国国家自然科学基金;
关键词
Electret; Transdermal drug delivery; Charge storage stability; Porous polytetrafluoroethylene; Polypropylene; DRUG-DELIVERY;
D O I
10.1016/j.elstat.2009.01.013
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
In this paper, PP/porous PTFE/PP electret, pressure sensitive adhesive PP/porous PTFE/PP electret and PP/porous PTFE/PP electret drug transdermal patch were prepared. By means of the surface potential decaying measurement and thermal discharge method, the charged storage stability was compared among them. The results indicated that (1) negative PP/porous PTFE/PP electret could still hold 93.4% of its initial surface potential when it was kept at RT for 16 days and exhibited better charge storage stability than positive electret. (2) The humidity almost had no influence in the charge storage stability of the electret. (3) The positive and negative PP/porous PTFE/PP adhesive electret could respectively hold 87.5% and 75.6% of their initial surface potential when being kept at room temperature for 13 days. The adhesive had a little influence in the charge storage stability of the electret. (4) Both the negative and positive PP/porous PTFE/PP electret drug transdermal patch had excellent charge storage stability. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:412 / 416
页数:5
相关论文
共 14 条
[1]   THERMAL CURRENTS FROM CORONA CHARGED MYLAR [J].
CRESWELL, RA ;
PERLMAN, MM .
JOURNAL OF APPLIED PHYSICS, 1970, 41 (06) :2365-&
[2]   Enhancing effect of electret on transdermal drug delivery [J].
Cui, LL ;
Jiang, J ;
Zhang, L ;
Song, CR ;
Zhao, WQ ;
Lin, JM .
JOURNAL OF ELECTROSTATICS, 2001, 51 (1-4) :153-158
[3]  
FELDSTEIN MM, 1995, P 1 WORLD M APGI APV, P683
[4]  
JIANG J, 2001, ACAD J SEC MIL MED U, V22, P401
[5]   Iontophoretic drug delivery [J].
Kalia, YN ;
Naik, A ;
Garrison, J ;
Guy, RH .
ADVANCED DRUG DELIVERY REVIEWS, 2004, 56 (05) :619-658
[6]   Photostimulated discharge in electret polymers:: an alternative approach for investigating deep traps [J].
Mellinger, A ;
González, FC ;
Gerhard-Multhaupt, R .
IEEE TRANSACTIONS ON DIELECTRICS AND ELECTRICAL INSULATION, 2004, 11 (02) :218-226
[7]  
Peter L., 1996, EUR J PHARM SCI, V4, P175
[8]   Electrets: recent developments [J].
Sessler, GM .
JOURNAL OF ELECTROSTATICS, 2001, 51 (1-4) :137-145
[9]  
SESSLER GM, 1999, GERHARD MULTHAUPT
[10]  
Van Turnhout J, 1999, ELECTRETS, V1