Eosinophilic fasciitis associated with hypereosinophilia, abnormal bone-marrow karyotype and inversion of chromosome 5

被引：3

作者：

Ferguson, J. S. ^{[1
]}

Bosworth, J. ^{[2
]}

Min, T. ^{[4
]}

Mercieca, J. ^{[2
]}

Holden, C. A. ^{[3
]}

机构：

[1] St George Hosp, Dept Dermatol, London, England

[2] St Helier Hosp, Dept Haematol, London, England

[3] St Helier Hosp, Dept Dermatol, London, England

[4] Royal Marsden NHS Trust, Inst Canc Res, Dept Cytogenet, London, England

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 2014年 / 39卷 / 02期

关键词：

CELLULITIS; PATIENT;

D O I：

10.1111/ced.12228

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report the case of a male patient presenting with eosinophilia, pulmonary oedema and eosinophilic fasciitis (EF). He had the classic clinical appearance and magnetic resonance imaging of EF. Cytogenetic analysis of the bone marrow revealed a previously undescribed pericentric inversion of chromosome 5. Overall, the presentation was consistent with a diagnosis of chronic eosinophilic leukaemia, not otherwise specified (CEL-NOS). Dermatologists should consult a haematologist in cases of EF, in order to rule out possible haematological malignancies.

引用

页码：150 / 153

页数：4

共 2 条

[1] Eosinophilic folliculitis: an important differential diagnosis after allogeneic bone-marrow transplant
Fraser, S. J.
Benton, E. C.
Roddie, P. H.
Krajewski, A. S.
Goodlad, J. R.
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2009, 34 (03) : 369 - 371
[2] A case of acute lymphoblastic leukemia with additional chromosomes X and 5 associated with a Philadelphia chromosome in the bone marrow
Durmaz, Burak
Durmaz, Asude Alpman
Karaca, Emin
Saydam, Guray
Cogulu, Ozgur
Ozkinay, Ferda
TURKISH JOURNAL OF HEMATOLOGY, 2010, 27 (04) : 299 - 302

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