Mechanism on Polarity Sorting of Actin Bundles Formed with Polycations

被引:5
|
作者
Shikinaka, Kazuhiro [1 ]
Kakugo, Akira [1 ]
Osada, Yoshihito [1 ]
Gong, Han Ping [1 ]
机构
[1] Hokkaido Univ, Grad Sch Sci, Dept Life Sci, Sapporo, Hokkaido 0600810, Japan
关键词
GROWTH CONES; F-ACTIN; ARP2/3; COMPLEX; IN-VITRO; MYOSIN; FILAMENTS; DYNAMICS; MOTILITY; PARACRYSTALS; LAMELLIPODIA;
D O I
10.1021/la803103k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this paper we explored factors that determine the polarity of an Actin bundle formed with polycation through electrostatic interaction. We found that the polarity decreases with an increase in the polycation concentration while it hardly depends on the KCl salt concentration. Additionally, the polarity of the Actin bundle increases with an increase in the degree of polymerization of the polycation at a constant polymer concentration. From these results we proposed that the kinetics of nuclei formation determines the polarity of the Actin bundle.
引用
收藏
页码:1554 / 1557
页数:4
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