Thrombotic microangiopathies: Similar presentations, different therapies

被引:6
作者
Appel, Gerald B. [1 ,2 ]
机构
[1] New York Presbyterian Hosp, Glomerular Ctr, New York, NY 10065 USA
[2] Columbia Univ, Coll Phys & Surg, New York, NY 10027 USA
关键词
HEMOLYTIC-UREMIC SYNDROME; ANTIPHOSPHOLIPID-ANTIBODY-SYNDROME; COMPLEMENT INHIBITOR ECULIZUMAB; VON-WILLEBRAND-FACTOR; THROMBOCYTOPENIC PURPURA; PLASMA-EXCHANGE; RECURRENT MISCARRIAGE; PATHOGENESIS; RITUXIMAB; GERMANY;
D O I
10.3949/ccjm.84gr.17001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Thrombotic thrombocytopenic purpura, Shiga toxin hemolytic uremic syndrome, atypical hemolytic uremic syndrome, and antiphospholipid syndrome are thrombotic microangiopathies that present similarly but arise from different causes. Management depends on distinguishing them promptly and providing targeted therapy.
引用
收藏
页码:114 / 130
页数:8
相关论文
共 35 条
[1]  
[Anonymous], 2011, PRESCR INF
[2]   Pathogenesis of the C3 glomerulopathies and reclassification of MPGN [J].
Bomback, Andrew S. ;
Appel, Gerald B. .
NATURE REVIEWS NEPHROLOGY, 2012, 8 (11) :634-642
[3]   CURRENT CONCEPTS - ESCHERICHIA-COLI O157-H7 AND THE HEMOLYTIC-UREMIC SYNDROME [J].
BOYCE, TG ;
SWERDLOW, DL ;
GRIFFIN, PM .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (06) :364-368
[4]   A systematic review of randomized controlled trials for plasma exchange in the treatment of thrombotic thrombocytopenic purpura [J].
Brunskill, S. J. ;
Tusold, A. ;
Benjamin, S. ;
Stanworth, S. J. ;
Murphy, M. F. .
TRANSFUSION MEDICINE, 2007, 17 (01) :17-35
[5]  
Canaud G, 2014, NEW ENGL J MED, V371, P1554, DOI [10.1056/NEJMoa1312890, 10.1056/NEJMc1410247]
[6]   A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome [J].
Crowther, MA ;
Ginsberg, JS ;
Julian, J ;
Denburg, J ;
Hirsh, J ;
Douketis, J ;
Laskin, C ;
Fortin, P ;
Anderson, D ;
Kearon, C ;
Clarke, A ;
Geerts, W ;
Forgie, M ;
Green, D ;
Costantini, L ;
Yacura, W ;
Wilson, S ;
Gent, M ;
Kovacs, MJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (12) :1133-1138
[7]   Lupus anticoagulants and the risk of a first episode of deep venous thrombosis [J].
De Groot, PG ;
Lutters, B ;
Derksen, RHWM ;
Lisman, T ;
Meijers, JCM ;
Rosendaal, FR .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2005, 3 (09) :1993-1997
[8]   INFECTIOUS-DISEASES ASSOCIATED WITH COMPLEMENT DEFICIENCIES [J].
FIGUEROA, JE ;
DENSEN, P .
CLINICAL MICROBIOLOGY REVIEWS, 1991, 4 (03) :359-395
[9]   Epidemic Profile of Shiga-Toxin-Producing Escherichia coli O104:H4 Outbreak in Germany [J].
Frank, Christina ;
Werber, Dirk ;
Cramer, Jakob P. ;
Askar, Mona ;
Faber, Mirko ;
an der Heiden, Matthias ;
Bernard, Helen ;
Fruth, Angelika ;
Prager, Rita ;
Spode, Anke ;
Wadl, Maria ;
Zoufaly, Alexander ;
Jordan, Sabine ;
Kemper, Markus J. ;
Follin, Per ;
Muller, Luise ;
King, Lisa A. ;
Rosner, Bettina ;
Buchholz, Udo ;
Stark, Klaus ;
Krause, Gerard .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (19) :1771-1780
[10]  
Gargau M, 2012, CLIN KIDNEY J, V5, P1