OBJECTIVES: Traditional hazards such as poor sanitation currently account for most of Africa's environmentally related disease burden. However, with rapid development absent appropriate safeguards for environment and health, modern environmental health hazards (MEHHs) may emerge as critical contributors to the continent's disease burden. We review recent evidence of human exposure to and health effects from MEHHs, and their occurrence in environmental media and consumer products. Our purpose is to highlight the growing significance of these hazards as African countries experience urbanization, industrial growth, and development. DATA SOURCES: We reviewed published epidemiologic, exposure, and environmental studies of chemical agents such as heavy metals and pesticides. DATA SYNTHESIS: The body of evidence demonstrates ongoing environmental releases of MEHHs and human exposures sometimes at toxicologically relevant levels. Several sources of MEHHs in environmental media have been identified, including natural resource mining and processing and automobile exhaust. Biomonitoring studies provided direct evidence of human exposure to metals such as mercury and lead and pesticides such as p,p'-dichlorodiphenyltrichloroethane (DDT) and organophosphates. Land and water resource pollution and industrial air toxics are areas of significant data gaps, notwithstanding the presence of several emitting sources. CONCLUSION: Unmitigated MEHH releases and human exposure have implications for Africa's disease burden. For Africans encumbered by conditions such as malnutrition that impair resilience to toxicologic challenges, the burden may be higher. A shift in public health policy toward accommodating the emerging diversity in Africa's environmental health issues is necessary to successfully alleviate the burden of avoidable ill health and premature death for all its communities now and in the future.
机构:
South African Med Res Council, Environm & Hlth Res Unit, Johannesburg, South Africa
Univ Witwatersrand, Sch Publ Hlth, Fac Hlth Sci, Johannesburg, South Africa
Univ Johannesburg, Environm Hlth Dept, Fac Hlth Sci, Johannesburg, South Africa
South African Med Res Council, Hlth Clin Bldg,Corner Beit & Sherwell St, ZA-2028 Johannesburg, South AfricaSouth African Med Res Council, Environm & Hlth Res Unit, Johannesburg, South Africa
Mathee, Angela
Barnes, Brendon
论文数: 0引用数: 0
h-index: 0
机构:
Univ Johannesburg, Psychol Dept, Fac Humanities, Johannesburg, South AfricaSouth African Med Res Council, Environm & Hlth Res Unit, Johannesburg, South Africa
Barnes, Brendon
Naidoo, Shan
论文数: 0引用数: 0
h-index: 0
机构:
Univ Witwatersrand, Sch Publ Hlth, Fac Hlth Sci, Johannesburg, South AfricaSouth African Med Res Council, Environm & Hlth Res Unit, Johannesburg, South Africa
Naidoo, Shan
Swart, Andre
论文数: 0引用数: 0
h-index: 0
机构:
Univ Johannesburg, Environm Hlth Dept, Fac Hlth Sci, Johannesburg, South AfricaSouth African Med Res Council, Environm & Hlth Res Unit, Johannesburg, South Africa
Swart, Andre
Rother, Hanna-Andrea
论文数: 0引用数: 0
h-index: 0
机构:
Univ Johannesburg, Psychol Dept, Fac Humanities, Johannesburg, South Africa
Univ Cape Town, Sch Publ Hlth & Family Med, Cape Town, South AfricaSouth African Med Res Council, Environm & Hlth Res Unit, Johannesburg, South Africa
机构:
Univ Sao Paulo, Inst Quim Sao Carlos, Sao Carlos, SP, Brazil
Inst Nacl Ciencia & Tecnol Bioanalit, Campinas, SP, Brazil
Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USAUniv Sao Paulo, Inst Quim Sao Carlos, Sao Carlos, SP, Brazil
Morbioli, Giorgio Gianini
Carrilho, Emanuel
论文数: 0引用数: 0
h-index: 0
机构:
Univ Sao Paulo, Inst Quim Sao Carlos, Sao Carlos, SP, Brazil
Inst Nacl Ciencia & Tecnol Bioanalit, Campinas, SP, BrazilUniv Sao Paulo, Inst Quim Sao Carlos, Sao Carlos, SP, Brazil
Carrilho, Emanuel
Luiz Vianna, Fernanda Sales
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Clin Porto Alegre, Sistema Nacl Informacao Agentes Teratogen SIAT, Porto Alegre, RS, Brazil
Univ Fed Rio Grande do Sul, Inst Biociencias, Dept Genet, Programa Posgrad Genet & Biol Mol, Porto Alegre, RS, BrazilUniv Sao Paulo, Inst Quim Sao Carlos, Sao Carlos, SP, Brazil
Luiz Vianna, Fernanda Sales
da Silva, Andre Anjos
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Clin Porto Alegre, Sistema Nacl Informacao Agentes Teratogen SIAT, Porto Alegre, RS, Brazil
UNIVATES Univ, Lajeado, RS, BrazilUniv Sao Paulo, Inst Quim Sao Carlos, Sao Carlos, SP, Brazil
da Silva, Andre Anjos
Schuler-Faccini, Lavinia
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Clin Porto Alegre, Sistema Nacl Informacao Agentes Teratogen SIAT, Porto Alegre, RS, Brazil
Univ Fed Rio Grande do Sul, Inst Biociencias, Dept Genet, Programa Posgrad Genet & Biol Mol, Porto Alegre, RS, BrazilUniv Sao Paulo, Inst Quim Sao Carlos, Sao Carlos, SP, Brazil
机构:
Univ North Carolina Chapel Hill, Curriculum Toxicol & Environm Med, Chapel Hill, NC USAUniv North Carolina Chapel Hill, Curriculum Toxicol & Environm Med, Chapel Hill, NC USA