Functional DNA nanomaterials for sensing and imaging in living cells

被引：60

作者：

Torabi, Seyed-Fakhreddin ^{[1
]}

Lu, Yi ^{[1
,2
]}

机构：

[1] Univ Illinois, Dept Biochem, Urbana, IL 61801 USA

[2] Univ Illinois, Dept Chem, Urbana, IL 61801 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2014年 / 28卷

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

RESONANCE ENERGY-TRANSFER; UP-CONVERSION NANOPARTICLES; PHOTON UPCONVERTING NANOPARTICLES; TRANSFER APTASENSOR; MESSENGER-RNA; FLUORESCENCE; STRATEGY; EMISSION; APTAMERS; SENSORS;

D O I：

10.1016/j.copbio.2013.12.011

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent developments in integrating high selectivity of functional DNA, such as DNAzymes and aptamers, with efficient DNA delivery into cells by gold nanoparticles or superior near-infrared optical properties of upconversion nanoparticles are reviewed. Their applications in sensing and imaging small organic metabolites, toxins, metal ions, pH, DNA, RNA, proteins, and pathogens are summarized. The advantages and future directions of these functional DNA materials are discussed.

引用

页码：88 / 95

页数：8