A genetic analysis of brain volumes and IQ in children

被引:31
|
作者
van Leeuwen, Marieke [1 ]
Peper, Jiska S. [2 ]
van den Berg, Stephanie M. [3 ]
Brouwer, Rachel M. [2 ]
Pol, Hilleke E. Hulshoff [2 ]
Kahn, Rene S. [2 ]
Boomsma, Dorret I. [1 ]
机构
[1] Vrije Univ Amsterdam, Dept Biol Psychol, NL-1081 BT Amsterdam, Netherlands
[2] Univ Med Ctr, Rudolf Magnus Inst Neurosci, Dept Psychiat, NL-3584 CX Utrecht, Netherlands
[3] Univ Utrecht, Fac Vet Med, Utrecht, Netherlands
关键词
White matter volume; Gray matter volume; Intelligence; Twin study; Children; COGNITIVE-ABILITY; WHITE-MATTER; SNAP-25; GENE; MR-IMAGES; INTELLIGENCE; CHILDHOOD; SIZE; ASSOCIATION; FAMILY; GRAY;
D O I
10.1016/j.intell.2008.10.005
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension. perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes. Crown Copyright (C) 2008 Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:181 / 191
页数:11
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