1-Amino-2-hydrazinobenzimidazole and its reactions with some carbonyl compounds

被引：4

作者：

Kuz'menko, T. A. ^{[1
]}

Kuz'menko, V. V. ^{[1
]}

Divaeva, L. N. ^{[1
]}

Morkovnik, A. S. ^{[1
]}

Borodkin, G. S. ^{[1
]}

机构：

[1] Southern Fed Univ, Res Inst Phys & Organ Chem, Rostov Na Donu 344090, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 50卷 / 05期

关键词：

ADENOSINE RECEPTOR ANTAGONISTS; OXIDATION;

D O I：

10.1134/S1070428014050182

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Amino-2-hydrazinobenzimidazole was obtained for the first time by treating 1-aminobenzimidazole-2-sulfonic acid with hydrazine hydrate. This compound readily condensed with aromatic aldehydes involving both amino groups. The condensation with 2,4-pentanedione affords 1-amino-2-(3,5-dimethylpyrazol-1-yl)benzimidazole, and with alpha-ketoacids in glacial acetic acid yields mixtures of 10-acetylamino-3-R-1,2,4-triazino[4,3-a]benzimidazol-4(10H)-ones and 4-amino-2-R-1,2,4-triazino[2,3-a]benzimidazol-3(4H)-ones.

引用

页码：729 / 735

页数：7

共 23 条

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