Effects of soybean oligosaccharides on antioxidant enzyme activities and insulin resistance in pregnant women with gestational diabetes mellitus

被引:37
作者
Fei, Bei-bei [1 ]
Ling, Li [1 ]
Hua, Chen [2 ]
Ren, Shu-yan [3 ]
机构
[1] Soochow Univ, Affiliated Hosp 2, Dept Gynecol & Obstet, Suzhou 215004, Peoples R China
[2] Soochow Univ, Affiliated Hosp 2, Dept Emergency, Suzhou 215004, Peoples R China
[3] Suzhou Municipal Hosp, Clin Nutr, Suzhou 215002, Peoples R China
关键词
Soybean oligosaccharides; Gestational diabetes mellitus; Antioxidant enzyme; Insulin resistance; CARDIOMYOCYTE APOPTOSIS; OXIDATIVE STRESS;
D O I
10.1016/j.foodchem.2014.02.106
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The effects of soybean oligosaccharides (SBOS) on antioxidant enzyme activities and insulin resistance in pregnant women with gestational diabetes mellitus (GDM) were investigated. Ninety-seven pregnant women with GDM were randomly divided into two groups, the control group (51 cases) and the SBOS group (46 cases). Before the group separation, the blood sugar level in patients was maintained stable by regular diet and insulin treatment. The control group was continued with the insulin treatment, while the SBOS group was treated with the combination of insulin and SBOS. Results showed that SBOS were able to reduce oxidative stress and alleviate insulin resistance in pregnant women with GDM, which indicates that SBOS may play an important role in the control of GDM complications. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:429 / 432
页数:4
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