Effects of soybean oligosaccharides on antioxidant enzyme activities and insulin resistance in pregnant women with gestational diabetes mellitus

被引：37

作者：

Fei, Bei-bei ^{[1
]}

Ling, Li ^{[1
]}

Hua, Chen ^{[2
]}

Ren, Shu-yan ^{[3
]}

机构：

[1] Soochow Univ, Affiliated Hosp 2, Dept Gynecol & Obstet, Suzhou 215004, Peoples R China

[2] Soochow Univ, Affiliated Hosp 2, Dept Emergency, Suzhou 215004, Peoples R China

[3] Suzhou Municipal Hosp, Clin Nutr, Suzhou 215002, Peoples R China

来源：

FOOD CHEMISTRY | 2014年 / 158卷

关键词：

Soybean oligosaccharides; Gestational diabetes mellitus; Antioxidant enzyme; Insulin resistance; CARDIOMYOCYTE APOPTOSIS; OXIDATIVE STRESS;

D O I：

10.1016/j.foodchem.2014.02.106

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The effects of soybean oligosaccharides (SBOS) on antioxidant enzyme activities and insulin resistance in pregnant women with gestational diabetes mellitus (GDM) were investigated. Ninety-seven pregnant women with GDM were randomly divided into two groups, the control group (51 cases) and the SBOS group (46 cases). Before the group separation, the blood sugar level in patients was maintained stable by regular diet and insulin treatment. The control group was continued with the insulin treatment, while the SBOS group was treated with the combination of insulin and SBOS. Results showed that SBOS were able to reduce oxidative stress and alleviate insulin resistance in pregnant women with GDM, which indicates that SBOS may play an important role in the control of GDM complications. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：429 / 432

页数：4

共 21 条

[1] Artemisia afra Jacq. Ameliorates Oxidative Stress in the Pancreas of Streptozotocin-Induced Diabetic Wistar Rats
Afolayan, Anthony Jide
Sunmonu, Taofik Olatunde
[J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2011, 75 (11) : 2083 - 2086
[2] Amer Diabet Assoc, 2011, DIABETES CARE, V34, pS11, DOI [10.2337/dc10-S062, 10.2337/dc14-S081, 10.2337/dc11-S011, 10.2337/dc13-S011, 10.2337/dc13-S067, 10.2337/dc12-s064, 10.2337/dc11-S062, 10.2337/dc10-S011, 10.2337/dc12-s011]
[3] A Combination of Two Antioxidants (An SOD Mimic and Ascorbate) Produces a Pro-Oxidative Effect Forcing Escherichia coli to Adapt Via Induction of oxyR Regulon
Batinic-Haberle, Ines
Rajic, Zrinka
Benov, Ludmil
[J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2011, 11 (04) : 329 - 340
[4] Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis
Bellamy, Leanne
Casas, Juan-Pablo
Hingorani, Aroon D.
Williams, David
[J]. LANCET, 2009, 373 (9677) : 1773 - 1779
[5] Effect of soybean oligosaccharides on blood lipid, glucose levels and antioxidant enzymes activity in high fat rats
Chen, Hua
Liu Li-jun
Zhu Jian-jun
Xu Bo
Li Rui
[J]. FOOD CHEMISTRY, 2010, 119 (04) : 1633 - 1636
[6] Chen Tian-jiao, 2005, Beijing Da Xue Xue Bao Yi Xue Ban, V37, P90
[7] Edeas Marvin, 2009, Journal de la Societe de Biologie, V203, P271, DOI 10.1051/jbio:2009031
[8] Espinosa-Martos I, 2006, NUTR HOSP, V21, P92
[9] Therapeutic strategies by modulating oxygen stress in cancer and inflammation
Fang, Jun
Seki, Takahiro
Maeda, Hiroshi
[J]. ADVANCED DRUG DELIVERY REVIEWS, 2009, 61 (04) : 290 - 302
[10] Chemical composition analysis of soybean oligosaccharides and its effect on ATPase activities in hyperlipidemic rats
Hua Chen
Liu Li-jun
Zhu Jian-jun
Xu Bo
Li Rui
[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2010, 46 (02) : 229 - 231

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