Synthesis, Characterization and Antioxidant Activity Evaluation of some 1,3,4-thiadiazole and 1,3,4-oxadiazole compounds

被引：0

作者：

Barbuceanu, Stefania-Felicia ^{[1
]}

Ilies, Diana Carolina ^{[1
]}

Radulescu, Valeria ^{[1
]}

Socea, Laura-Ileana ^{[1
]}

Draghici, Constantin ^{[2
]}

Saramet, Gabriel ^{[3
]}

机构：

[1] Univ Med & Pharm Carol Davila, Dept Organ Chem, Fac Pharm, Bucharest 020956, Romania

[2] Organ Chem Ctr Costin D Nenitzescu, Bucharest 060023, Romania

[3] Univ Med & Pharm Carol Davila, Dept Pharmaceut Technol, Fac Pharm, Bucharest 020956, Romania

来源：

REVISTA DE CHIMIE | 2014年 / 65卷 / 10期

关键词：

1,3,4-thiadiazole; 1,3,4-oxadiazole; antioxidant activity; BIOLOGICAL EVALUATION; HETEROCYCLIC-COMPOUNDS; ANTIBACTERIAL ACTIVITY; IN-VITRO; DERIVATIVES; 1,2,4-TRIAZOLE; DIPHENYLSULFONE; ANTIFUNGAL;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This paper presents synthesis of new compounds from 1,3,4-thiadiazole and 1,3,4-oxadiazole class obtained by cyclization of some hydrazinecarbothioamides containing arylsuffonylphenyl and 2,4-difiuorophenyl moieties that were described in a previous paper [221 The structures of these compounds were confirmed by elemental analysis and spectral techniques (IR, H-1-NMR, C-13-NMR, UV). The 1,3,4-thiadiazoles and 1,3,4-oxadiazoles were tested for their antioxidant activity by DPPH method.

引用

页码：1172 / 1175

页数：4

共 30 条

[1]

Amir Mohammad, 2007, Acta Pharmaceutica (Zagreb), V57, P31, DOI 10.2478/v10007-007-0003-y

[2] Identification of a Novel Series of N-Phenyl-5-[(2phenylbenzimidazol-1-yl)methyl]-1,3,4-oxadiazol-2-amines as Potent Antioxidants and Radical Scavengers [J].

Ayhan-Kilcigil, Gulgun ;

Kus, Canan ;

Coban, Tulay ;

Ozdamar, Elcin D. ;

Can-Eke, Benay .

ARCHIV DER PHARMAZIE, 2014, 347 (04) :276-282

[3]

Barbuceanu SF, 2008, REV CHIM-BUCHAREST, V59, P304

[4] Synthesis and Antioxidant Activity Evaluation of New Compounds from Hydrazinecarbothioamide and 1,2,4-Triazole Class Containing Diarylsulfone and 2,4-Difluorophenyl Moieties [J].

Barbuceanu, Stefania-Felicia ;

Ilies, Diana Carolina ;

Saramet, Gabriel ;

Uivarosi, Valentina ;

Draghici, Constantin ;

Radulescu, Valeria .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 15 (06) :10908-10925

[5] New heterocyclic compounds from 1,2,4-triazole and 1,3,4-thiadiazole class bearing diphenylsulfone moieties. Synthesis, characterization and antimicrobial activity evaluation [J].

Barbuceanu, Stefania-Felicia ;

Saramet, Gabriel ;

Almajan, Gabriela Laura ;

Draghici, Constantin ;

Barbuceanu, Florica ;

Bancescu, Gabriela .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 49 :417-423

[6]

Barbuceanu SF, 2011, REV CHIM-BUCHAREST, V62, P308

[7]

Barbuceanu SF, 2010, REV CHIM-BUCHAREST, V61, P1017

[8] Sulfonamide-1,2,4-thiadiazole Derivatives as Antifungal and Antibacterial Agents: Synthesis, Biological Evaluation, Lipophilicity, and Conformational Studies [J].

Camoutsis, Charalabos ;

Geronikaki, Athina ;

Ciric, Ana ;

Sokovic, Marina ;

Zoumpoulakis, Panagiotis ;

Zervou, Maria .

CHEMICAL & PHARMACEUTICAL BULLETIN, 2010, 58 (02) :160-167

[9] Evaluation of antioxidant property of extract and fractions obtained from a red alga, Polysiphonia urceolata [J].

Duan, XJ ;

Zhang, WW ;

Li, XM ;

Wang, BG .

FOOD CHEMISTRY, 2006, 95 (01) :37-43

[10] Synthesis, characterization, and in vitro antimicrobial activities of 5-alkenyl/hydroxyalkenyl-2-phenylamine-1,3,4-oxadiazoles and thiadiazoles [J].

Farshori, Nida N. ;

Banday, Mudasir R. ;

Ahmad, Anis ;

Khan, Asad U. ;

Rauf, Abdul .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (06) :1933-1938

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