Comparison of pericranium and eggshell as space fillers used in combination with guided bone regeneration: An experimental study

被引:34
作者
Dupoirieux, L [1 ]
Neves, M [1 ]
Pourquier, D [1 ]
机构
[1] Inst Expt Surg, Montpellier, France
关键词
D O I
10.1016/S0278-2391(00)80013-0
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Purpose: The purpose of the study was to determine the potential adjunctive role of 2 space fillers, used in combination with guided tissue regeneration, on bone regeneration in rat skull defects. Materials and Methods: The study was conducted on 45 adult Wistar rats. A bilateral 6-mm-wide full-thickness skull defect was created in the parietal region of each animal. The right defect was chosen as the experiment site, and the left defect was left empty as a control. Each experiment sire was covered by an inner and outer polytetrafluoroethylene membrane. The 45 rats were divided into 3 groups; no space filler between the 2 membranes was used in group I (n = 15), a free pericranial autograft was used as a space filler between the 2 membranes in group II (n = IS), and purified eggshell powder was used as space filler between the 2 membranes in group III (n = 15). Five animals in each group were killed at 15, 30, and 90 days. The harvested specimens were subjected to contact radiography and standard microscopic examination, and the rates of osteogenesis were assessed by a semiquantitative method. Results: No evidence of bone regeneration was seen in any animals of the three groups at IS days. At 30 days, bone regeneration only appeared in group I (P >.05). Ar 90 days, complete bone regeneration was observed in the group I In 3 of 5 animals (P <.05). In group II, the pericranial graft showed no osteogenic properties. In group III, the eggshell powder showed no resorption, but no osteoconduction was noticed. Conclusions: Although the osteogenic mechanism of guided tissue regeneration is not clear, this study suggests that the physical properties of the membrane are more important than the use of an adjunctive space filler.
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页码:40 / 46
页数:7
相关论文
共 26 条
[1]  
BOSCH C, 1995, CLEFT PALATE-CRAN J, V32, P311, DOI 10.1597/1545-1569(1995)032<0311:GBRICB>2.3.CO
[2]  
2
[3]   PERIODONTAL REGENERATION OF HUMAN INTRABONY DEFECTS WITH TITANIUM REINFORCED MEMBRANES - A CONTROLLED CLINICAL-TRIAL [J].
CORTELLINI, P ;
PRATO, GP ;
TONETTI, MS .
JOURNAL OF PERIODONTOLOGY, 1995, 66 (09) :797-803
[4]   OSTEOPROMOTION FOR CRANIOPLASTY - AN EXPERIMENTAL-STUDY IN RATS USING A MEMBRANE TECHNIQUE [J].
DAHLIN, C ;
ALBERIUS, P ;
LINDE, A .
JOURNAL OF NEUROSURGERY, 1991, 74 (03) :487-491
[5]   HEALING OF BONE DEFECTS BY GUIDED TISSUE REGENERATION [J].
DAHLIN, C ;
LINDE, A ;
GOTTLOW, J ;
NYMAN, S .
PLASTIC AND RECONSTRUCTIVE SURGERY, 1988, 81 (05) :672-676
[6]   Bone regeneration in extraction sites after immediate placement of an e-PTFE membrane with or without a biomaterial - A report on 12 consecutive cases [J].
Dies, F ;
Etienne, D ;
Abboud, NB ;
Ouhayoun, JP .
CLINICAL ORAL IMPLANTS RESEARCH, 1996, 7 (03) :277-285
[7]   POWDERED EGGSHELL - A PILOT-STUDY ON A NEW BONE SUBSTITUTE FOR USE IN MAXILLOFACIAL SURGERY [J].
DUPOIRIEUX, L ;
POURQUIER, D ;
SOUYRIS, F .
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, 1995, 23 (03) :187-194
[8]  
Fatah M F, 1992, J Craniofac Surg, V3, P170, DOI 10.1097/00001665-199211000-00009
[9]   TEMPORAL DYNAMICS OF HEALING IN RABBIT CRANIAL DEFECTS USING GUIDED BONE REGENERATION [J].
HAMMERLE, CHF ;
SCHMID, J ;
LANG, NP ;
OLAH, AJ .
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 1995, 53 (02) :167-174
[10]   Periodontal repair in intrabony defects treated with a calcium carbonate implant and guided tissue regeneration [J].
Kim, CK ;
Choi, EJ ;
Cho, KS ;
Chai, JK ;
Wikesjo, UME .
JOURNAL OF PERIODONTOLOGY, 1996, 67 (12) :1301-1306