Analysis of Antigens of Mycobacterium leprae by Interaction to Sera IgG, IgM, and IgA Response to Improve Diagnosis of Leprosy

被引：13
|
作者：
Kumar, Avnish [1 ]
Parkash, Om [2 ]
Girdhar, Bhawneshwar K. [3 ]
机构：
[1] Dr Bhim Rao Ambedkar Univ, Sch Life Sci, Dept Biotechnol, Agra 282004, Uttar Pradesh, India
[2] Natl JALMA Inst Leprosy & Other Mycobacterial Dis, Dept Immunol, Agra 282001, Uttar Pradesh, India
[3] Shanti Manglik Hosp, Agra 282001, Uttar Pradesh, India
来源：
BIOMED RESEARCH INTERNATIONAL | 2014年 / 2014卷
关键词：
T-CELL RESPONSES; PHENOLIC GLYCOLIPID-I; M; LEPRAE; SEROLOGICAL DIAGNOSIS; POSTGENOMIC APPROACH; ANTIBODY-ACTIVITY; PROTEIN ANTIGENS; COSMID LIBRARY; FUSION PROTEIN; DDS TREATMENT;
D O I：
10.1155/2014/283278
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Till 2010, several countries have declared less than one leprosy patient among population of 10,000 and themselves feeling as eliminated from leprosy cases. However, new leprosy cases are still appearing from all these countries. In this situation one has to be confident to diagnose leprosy. This review paper highlighted already explored antigens for diagnosis purposes and finally suggested better combinations of protein antigens of M. leprae versus immunoglobulin as detector antibody to be useful for leprosy diagnosis.
引用
收藏
页数：10
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