Preparation of porous hydroxyapatite particles to be used as drug delivery systems

被引：6
作者：
Martins, MA [1 ]
Santos, C [1 ]
Costa, MEV [1 ]
Almeida, MM [1 ]
机构：
[1] Univ Aveiro, CICECO, Dept Ceram & Glass Engn, P-3810193 Aveiro, Portugal
来源：
ADVANCED MATERIALS FORUM II | 2004年 / 455-456卷
关键词：
hydroxyapatite; nanoparticles; porous particles; drug delivery; bioceramics;
D O I：
10.4028/www.scientific.net/MSF.455-456.353
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Porous apatite particles with an average diameter of 3-4 mum were produced by spray drying a suspension of apatite nanoparticles, which were previously obtained by precipitation in a calcium/citrate/phosphate solution. The high surface area of the porous particles indicates a highly porous structure. The so produced spray dried apatite particles have the capability to adsorb and release a model drug compound (salicylic acid) in solutions at physiological pH.
引用
收藏
页码：353 / 357
页数：5
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