New bioactive marine steroids from the Okinawan soft coral Clavularia viridis

被引：16

作者：

Watanabe, K ^{[1
]}

Iwashima, M ^{[1
]}

Iguchi, K ^{[1
]}

机构：

[1] TOKYO UNIV PHARM & LIFE SCI,SCH LIFE SCI,BIOORGAN CHEM LAB,HACHIOJI,TOKYO 19203,JAPAN

来源：

STEROIDS | 1996年 / 61卷 / 07期

关键词：

soft coral; Clavularia viridis; structure; X-ray crystallographic analysis; cell growth inhibition;

D O I：

10.1016/0039-128X(96)00077-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Eight new marine steroids were isolated from the Okinawan soft coral Clavularia viridis Quoy and Gaimard. Their structures were determined based on spectroscopic analysis, chemical conversion, and X-ray crystallographic analysis. Steroids 5 and 6 showed growth inhibition activity toward HeLa S3 cells and human diploid cells in vitro.

引用

页码：439 / 446

页数：8

共 7 条

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