Powder X-ray diffraction of levothyroxine sodium pentahydrate, C15H10I4NNaO4(H2O)5

被引:3
作者
Kaduk, J. A. [1 ]
Zhong, K. [2 ]
Blanton, T. N. [2 ]
Gates, S. [2 ]
Fawcett, T. G. [2 ]
机构
[1] IIT, Chicago, IL 60616 USA
[2] Int Ctr Diffract Data, 12 Campus Blvd, Newtown Sq, PA 19073 USA
关键词
levothyroxine sodium; Synthroid; density functional theory; Rietveld refinement;
D O I
10.1017/S0885715615000676
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The room-temperature crystal structure of levothyroxine sodium pentahydrate has been refined using synchrotron powder diffraction data. The compound crystallizes in space group P1 (#1) with a = 8.2489(4), b = 9.4868(5), c = 15.8298(6) angstrom, a = 84.1387(4), beta = 83.1560(3), gamma = 85.0482(3) deg, V = 1220.071(9) angstrom(3), and Z = 2. Hydrogen atoms (missing from the previously-reported structure) were included. (C) 2015 International Centre for Diffraction Data.
引用
收藏
页码:370 / 371
页数:2
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