Assessing General Versus Specific Liability for Externalizing Problems in Adolescence: Concurrent and Prospective Prediction of Symptoms of Conduct Disorder, ADHD, and Substance Use

被引：9

作者：

Perkins, Emily R. ^{[1
]}

Joyner, Keanan J. ^{[1
]}

Foell, Jens ^{[1
]}

Drislane, Laura E. ^{[2
]}

Brislin, Sarah J. ^{[3
]}

Frick, Paul J. ^{[4
,5
]}

Yancey, James R. ^{[6
,7
]}

Soto, Elia F. ^{[1
]}

Ganley, Colleen M. ^{[1
]}

Keel, Pamela K. ^{[1
]}

Sica, Claudio ^{[8
]}

Flor, Herta ^{[9
,10
]}

Nees, Frauke ^{[9
,11
]}

Banaschewski, Tobias ^{[12
]}

Bokde, Arun L. W. ^{[13
,14
]}

Desrivieres, Sylvane ^{[15
]}

Grigis, Antoine ^{[16
]}

Garavan, Hugh ^{[17
,18
]}

Gowland, Penny ^{[19
]}

Heinz, Andreas ^{[20
]}

Ittermann, Bernd ^{[21
]}

Martinot, Jean-Luc ^{[22
]}

Martinot, Marie-Laure Paillere ^{[22
,23
]}

Artiges, Eric ^{[22
,24
]}

Orfanos, Dimitri Papadopoulos ^{[16
]}

Poustka, Luise ^{[25
]}

Hohmann, Sarah ^{[12
]}

Froehner, Juliane H. ^{[26
,27
]}

Smolka, Michael N. ^{[26
,27
]}

Walter, Henrik ^{[20
]}

Whelan, Robert ^{[14
,28
]}

Schumann, Gunter ^{[29
,30
]}

Patrick, Christopher J. ^{[1
]}

机构：

[1] Florida State Univ, Dept Psychol, 1107 West Call St, Tallahassee, FL 32306 USA

[2] Sam Houston State Univ, Dept Psychol, Huntsville, TX 77340 USA

[3] Virginia Commonwealth Univ, Dept Psychol, Richmond, VA 23284 USA

[4] Louisiana State Univ, Dept Psychol, Baton Rouge, LA 70803 USA

[5] Australian Catholic Univ, Inst Learning Sci & Teacher Educ, Thebarton, Australia

[6] VA Salt Lake City Hlth Care Syst, Rocky Mt Network Mental Illness Res Educ & Clin C, Salt Lake City, UT USA

[7] Univ Utah, Dept Psychiat, Salt Lake City, UT 84112 USA

[8] Univ Firenze, Dept Hlth Sci, Florence, Italy

[9] Heidelberg Univ, Med Fac Mannheim, Dept Cognit & Clin Neurosci, Cent Inst Mental Hlth, Heidelberg, Germany

[10] Univ Mannheim, Dept Psychol, Mannheim, Germany

[11] Univ Med Ctr Schleswig Holstein Kiel, Inst Med Psychol & Med Sociol, Kiel, Germany

[12] Heidelberg Univ, Med Fac Mannheim, Cent Inst Mental Hlth, Dept Child & Adolescent Psychiat & Psychotherapy, Heidelberg, Germany

[13] Trinity Coll Dublin, Discipline Psychiat, Dublin, Ireland

[14] Trinity Coll Dublin, Trinity Coll Inst Neurosci, Dublin, Ireland

[15] Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England

[16] Univ Paris Saclay, NeuroSpin, CEA, Paris, France

[17] Univ Vermont, Dept Psychiat, Burlington, VT 05405 USA

[18] Univ Vermont, Dept Psychol, Burlington, VT 05405 USA

[19] Univ Nottingham Univ Pk, Sir Peter Mansfeld Imaging Ctr, Sch Phys & Astron, Nottingham, England

[20] Charite Univ Med Berlin, Dept Psychiat & Psychotherapy, Berlin, Germany

[21] Phys Tech Bundesanstalt, Dept Biomed Magnet Resonance, Braunschweig, Germany

[22] Univ Paris Saclay, INSERM U Trajectoires Dev Psychiat A10, Inst Natl Sante & Rech Med, Ecole Normale Super Paris Saclay,CNRS,Ctr Borelli, Gif Sur Yvette, France

[23] Sorbonne Univ, Pitie Salpetriere Hosp, AP HP, Dept Child & Adolescent Psychiat, Paris, France

[24] EPS Barthelemy Durand, Dept Psychiat, Etampes, France

[25] Univ Med Ctr Gottingen, Dept Child & Adolescent Psychiat & Psychotherapy, Gottingen, Germany

[26] Tech Univ Dresden, Dept Psychiat & Psychotherapy, Dresden, Germany

[27] Tech Univ Dresden, Neuroimaging Ctr, Dresden, Germany

[28] Trinity Coll Dublin, Dept Psychol, Dublin, Ireland

[29] Fudan Univ, Ctr Populat Neurosci & Stratified Med PONS, Inst Sci & Technol Brain Inspired Intelligence IS, Shanghai, Peoples R China

[30] Charite Univ Med Berlin, Ctr Populat Neurosci & Stratified Med PONS, Charite Mental Hlth, Dept Psychiat & Psychotherapy,CCM, Berlin, Germany

来源：

JOURNAL OF PSYCHOPATHOLOGY AND CLINICAL SCIENCE | 2022年 / 131卷 / 07期

基金：

英国医学研究理事会; 欧洲研究理事会; 美国国家卫生研究院; 爱尔兰科学基金会;

关键词：

disinhibition; callousness; adolescence; liability; externalizing; CALLOUS-UNEMOTIONAL TRAITS; OPPOSITIONAL DEFIANT DISORDER; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; ANTISOCIAL-BEHAVIOR; HIERARCHICAL TAXONOMY; ALCOHOL-USE; PSYCHOPATHOLOGY HITOP; PERSONALITY-TRAITS; INHIBITORY CONTROL; DISINHIBITION;

D O I：

10.1037/abn0000743

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

This study explored the generality versus specificity of two trait-liability factors for externalizing problems-disinhibition and callousness-in the concurrent and prospective prediction of symptoms of conduct disorder, attention-deficit/hyperactivity disorder (ADHD), and substance use (i.e., alcohol use disorder and history of illicit substance use). Disinhibition involves an impulsive, unrestrained cognitive-behavioral style; callousness entails a dispositional lack of social-emotional sensitivity. Participants were European adolescents from the multisite IMAGEN project who completed questionnaires and clinical interviews at ages 14 (N = 1,504, Mage = 14.41, 51.13% female) and 16 (N = 1,407, Mage = 16.46, 51.88% female). Disinhibition was related concurrently and prospectively to greater symptoms of conduct disorder, ADHD, and alcohol use disorder; higher scores on a general externalizing factor; and greater likelihood of having tried an illicit substance. Callousness was selectively related to greater conduct disorder symptoms. These findings indicate disinhibition confers broad liability for externalizing spectrum disorders, perhaps due to its affiliated deficits in executive function. In contrast, callousness appears to represent more specific liability for antagonistic (aggressive/exploitative) forms of externalizing, as exemplified by antisocial behavior. Results support the utility of developmental-ontogenetic and hierarchical-dimensional models of psychopathology and have important implications for early assessment of risk for externalizing problems. General Scientific Summary This study suggests that assessing dispositional traits of disinhibition and callousness in adolescence can provide important predictive information about later-emerging behavior problems. Further, these traitrisk factors differ in the specificity of their relations with externalizing psychopathology, with disinhibition promoting overall risk and callousness predicting risk for conduct problems in particular.

引用

页码：793 / 807

页数：15

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