Cell biology - Reeling CASK into the nucleus

被引：13

作者：

Bredt, DS ^{[1
]}

机构：

[1] Univ Calif San Francisco, Sch Med, Dept Physiol, San Francisco, CA 94143 USA

来源：

NATURE | 2000年 / 404卷 / 6775期

关键词：

D O I：

10.1038/35005208

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Cells send messages to their neighbours through ‘junctional complexes’, which link molecules on the cell surface to the cytoskeleton beneath. One of the proteins that forms these complexes, CASK, is now shown to travel from the cell surface to the nucleus, where it regulates gene expression by binding to DNA.

引用

页码：241 / 242

页数：2

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