A new compound with cytotoxic activities from the leaves of Panax ginseng CA Meyer

被引：8

作者：

Wang, Li Bo ^{[1
]}

Wu, Zhao Hua ^{[1
,2
]}

Gao, Hui Yuan ^{[1
]}

Huang, Jian ^{[1
]}

Sun, Bo Hang ^{[1
]}

Wu, Li Jun ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Peoples R China

[2] Mudanjiang Med Coll, Dept Pharmacol, Mudanjiang 157001, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2008年 / 19卷 / 07期

关键词：

Panax ginseng; 3,6,20(S)-Trihydroxy-12,23-epoxy-dammar-24-ene,6,20-Di-O-beta-D-glucopyranoside; Cytotoxic activity;

D O I：

10.1016/j.cclet.2008.05.017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new compound, 3,6,20(S)-trihydroxy-12,23-epoxydammar-24-ene,6,20-di-O-beta-D-glucopyranoside (1), was isolated from the leaves of Panax ginseng C. A. Meyer, whose structural elucidation was carried out by means of spectral analysis (including IR, HR-FAB-MS and NMR). This compound showed the moderate cytotoxic activities against U937 and HeLa cells by using the MTT method. (C) 2008 Li Jun Wu. Published by Elsevier B. V. on behalf of Chinese Chemical Society. All rights reserved.

引用

页码：837 / 840

页数：4

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