Interim estimates of the effectiveness of influenza vaccination against influenza-associated hospitalization in children in Hong Kong, 2015-16

被引：14

作者：

Cowling, Benjamin J. ^{[1
]}

Kwan, Mike Y. W. ^{[2
]}

Wong, Joshua S. C. ^{[2
]}

Feng, Shuo ^{[1
]}

Leung, Chi-Wai ^{[2
]}

Chan, Eunice L. Y. ^{[3
,4
]}

Chan, Kwok-Hung ^{[5
]}

Ng, Tak-Keung ^{[6
]}

To, Wing-Kin ^{[7
]}

Peiris, Malik J. S. ^{[1
,8
]}

Chiu, Susan S. ^{[3
,4
]}

机构：

[1] Univ Hong Kong, Li Ka Shing Fac Med, Sch Publ Hlth, WHO Collaborating Ctr Infect Dis Epidemiol & Cont, Hong Kong, Hong Kong, Peoples R China

[2] Princess Margaret Hosp, Dept Paediat & Adolescent Med, Hong Kong, Hong Kong, Peoples R China

[3] Univ Hong Kong, Dept Paediat & Adolescent Med, Queen Mary Hosp, Hong Kong, Hong Kong, Peoples R China

[4] Univ Hong Kong, Li Ka Shing Fac Med, Hong Kong, Hong Kong, Peoples R China

[5] Univ Hong Kong, Li Ka Shing Fac Med, Dept Microbiol, Hong Kong, Hong Kong, Peoples R China

[6] Princess Margaret Hosp, Dept Pathol, Hong Kong, Hong Kong, Peoples R China

[7] Yan Chai Hosp, Dept Pathol, Hong Kong, Hong Kong, Peoples R China

[8] Univ Hong Kong, Li Ka Shing Fac Med, Ctr Influenza Res, Hong Kong, Hong Kong, Peoples R China

来源：

INFLUENZA AND OTHER RESPIRATORY VIRUSES | 2017年 / 11卷 / 01期

关键词：

effectiveness; hospitalization; influenza; interim; pediatrics; vaccine; TEST-NEGATIVE DESIGN; UNITED-STATES;

D O I：

10.1111/irv.12399

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

From 1 September 2015 through 31 January 2016, we enrolled 2068 children 6 months to 17 years of age admitted to hospital with a febrile acute respiratory infection in our test-negative study. Information on receipt of 2015-16 northern hemisphere inactivated influenza vaccination was elicited from parents or legal guardians. Using conditional logistic regression adjusting for age and matching on calendar time, we estimated influenza vaccine effectiveness against hospitalization with influenza A or B to be 79.2% (95% confidence interval: 42.0%-92.4%). Annual influenza vaccination should be more widely used in children in Hong Kong.

引用

页码：61 / 65

页数：5

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