Evaluation of an epidemic of sporotrichosis in cats: 347 cases (1998-2001)

被引:150
作者
Schubach, TMP
Schubach, A
Okamoto, T
Barros, MBL
Figueiredo, FB
Cuzzi, T
Fialho-Monteiro, PC
Reis, RS
Perez, MA
Wanke, B
机构
[1] Fiocruz MS, Fundacao Oswaldo Cruz, Inst Pesquisas Clin Evandro Chagas, Serv Zoonoses, BR-21045900 Rio De Janeiro, Brazil
[2] Fiocruz MS, Fundacao Oswaldo Cruz, Inst Pesquisas Clin Evandro Chagas, Serv Micol, BR-21045900 Rio De Janeiro, Brazil
[3] Fiocruz MS, Fundacao Oswaldo Cruz, Inst Pesquisas Clin Evandro Chagas, Serv Infectol, BR-21045900 Rio De Janeiro, Brazil
[4] Fiocruz MS, Fundacao Oswaldo Cruz, Inst Pesquisas Clin Evandro Chagas, Serv Patol, BR-21045900 Rio De Janeiro, Brazil
[5] Fiocruz MS, Fundacao Oswaldo Cruz, Inst Pesquisas Clin Evandro Chagas, Serv Epidemiol, BR-21045900 Rio De Janeiro, Brazil
[6] Univ Fed Rio de Janeiro, Dept Med Prevent & Nucl Estudos Saude Colet, Rio De Janeiro, Brazil
来源
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION | 2004年 / 224卷 / 10期
关键词
D O I
10.2460/javma.2004.224.1623
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Objective-To evaluate characteristics of a large epidemic of sporotrichosis in cats. Design-Retrospective study. Animals-347 cats with naturally acquired infection with Sporothrix schenckii. Procedure-Medical records were reviewed for data regarding clinical, mycologic, histopathologic, and routine hematologic and serum biochemical findings; assays for FIV-specific antibodies and FeLV antigen; antifungal treatment; and follow-up. Results-Lesions varied from small papules to extensive zones of necrosis. Ten cats had no skin lesions, 114 had skin lesions at a single site, 86 had skin lesions in 2 sites, and 137 had skin lesions in 3 or more sites. Respiratory tract signs were observed in 154 cats and were the most frequent extracutaneous sign. Anemia, leukocytosis with neutrophilia, hypoalbuminemia, and hyperglobulinemia were the main blood abnormalities. Antibodies against FIV were detected in 28 cats, FeLV antigen was detected in 2 cats, and both were detected in 1 cat among 142 cats tested. During the study, 118 cats were lost to follow-up and 124 died. Of 266 cats that were treated, 68 were cured. Complete healing of the lesions was observed regardless of the presence of extracutaneous signs, general condition, treatment schedule, or coinfection with FIV. Conclusions and Clinical Relevance-Feline sporotrichosis was evident in subclinical to severe forms; however, cats can respond well to regular and prolonged antifungal treatment.
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收藏
页码:1623 / 1629
页数:7
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