The occurrence of quinolone and imidazole antibiotics in rivers in Central Taiwan

被引:5
|
作者
Lee, Wan-Ning [1 ]
Lin, Angela Yu-Chen [1 ]
Wang, Xiao-Huan [1 ]
机构
[1] Natl Taiwan Univ, Grad Inst Environm Engn, Taipei 106, Taiwan
关键词
HPLC-ESI-tandem MS; Solid-phase extraction; Quinolone antibiotics; Imidazole antibiotics; ENVIRONMENTAL RISK-ASSESSMENT; SOLID-PHASE EXTRACTION; LIQUID-CHROMATOGRAPHY; WASTE-WATER; FLUOROQUINOLONE ANTIBIOTICS; TREATMENT PLANTS; SEWAGE WATER; PHARMACEUTICALS; TRIMETHOPRIM; FATE;
D O I
10.1080/19443994.2013.826778
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
The occurrence of antibiotics in aquatic environments has been of increasing concern around the world due to their ability to alter the structure of microbial communities and to promote the development of antimicrobial-resistant pathogens. Six major rivers in Central Taiwan were investigated for the occurrence of the eight most frequently prescribed quinolone and imidazole antibiotics using solid-phase extraction followed by high performance liquid chromatography-electrospray ionization-tandem mass spectrometry. Nalidixic acid, flumequine, ofloxacin, dimetridazole, and metronidazole were detected at 0.8-192ng/L in the water samples. The three most frequently detected antibiotics at all sampling sites were metronidazole, nalidixic acid, and flumequine (detection frequency (n=24) 19 sites). The highest concentration of flumequine was detected at 192 +/- 6.5ng/L in the Old Zhuoshui River. Compared to the available predicted no-effect concentration data, the risk quotients of flumequine and ofloxacin were estimated to be close to one. The Old Zhuoshui and Beigang Rivers were shown to be the two most contaminated rivers with the nearby animal husbandries being the important source of contamination. The information provided here warrants future attention and is useful for the development of regulation and remediation strategies.
引用
收藏
页码:1143 / 1152
页数:10
相关论文
共 50 条
  • [1] Occurrence and fate of quinolone and fluoroquinolone antibiotics in a municipal sewage treatment plant
    Jia, Ai
    Wan, Yi
    Xiao, Yang
    Hu, Jianying
    WATER RESEARCH, 2012, 46 (02) : 387 - 394
  • [2] THE QUINOLONE ANTIBIOTICS
    WOOD, MJ
    CURRENT OPINION IN INFECTIOUS DISEASES, 1988, 1 (03) : 356 - 362
  • [3] Quinolone antibiotics
    Pham, Thu D. M.
    Ziora, Zyta M.
    Blaskovich, Mark A. T.
    MEDCHEMCOMM, 2019, 10 (10) : 1719 - 1739
  • [4] THE QUINOLONE ANTIBIOTICS
    SARAVANOS, K
    DUFF, P
    OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA, 1992, 19 (03) : 529 - 537
  • [5] THE QUINOLONE ANTIBIOTICS
    MANDELL, WF
    NEU, H
    CURRENT OPINION IN INFECTIOUS DISEASES, 1989, 2 (03) : 357 - 361
  • [6] Mineralogy and occurrence of glauconite in central Taiwan
    Chang, Shyun Sheng
    Shau, Yen Hong
    Wang, Ming Kuang
    Ku, Ching Teh
    Chiang, Po Neng
    APPLIED CLAY SCIENCE, 2008, 42 (1-2) : 74 - 80
  • [7] Evaluation and investigation of safety on headworks of rivers in Central Taiwan
    Chen, Feng-Wen
    Lin, Hsiij-Te
    Liu, Chen-Wuing
    Tan, Yih-Chi
    Taiwan Water Conservancy, 2012, 60 (04): : 26 - 40
  • [8] Occurrence of antibiotics and antibiotic resistant bacteria in subtropical urban rivers in Brazil
    Boger, Beatriz
    Surek, Monica
    Vilhena, Raquel de O.
    Fachi, Mariana M.
    Junkert, Allan M.
    Santos, Josiane M. M. F.
    Domingos, Eric L.
    Cobre, Alexandre de F.
    Momade, Danilo R.
    Pontarolo, Roberto
    JOURNAL OF HAZARDOUS MATERIALS, 2021, 402
  • [9] Occurrence of β-blockers and β-agonists in hospital effluents and their receiving rivers in southern Taiwan
    Yu, Tsung-Hsien
    Lin, Angela Yu-Chen
    Wang, Xiao-Huan
    Lin, Cheng-Fang
    DESALINATION AND WATER TREATMENT, 2011, 32 (1-3) : 49 - 56
  • [10] Occurrence and Transport of Tetracycline, Sulfonamide, Quinolone, and Macrolide Antibiotics in the Haihe River Basin, China
    Luo, Yi
    Xu, Lin
    Rysz, Michal
    Wang, Yuqiu
    Zhang, Hao
    Alvarez, Pedro J. J.
    ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2011, 45 (05) : 1827 - 1833