Unravelling Toxoplasma treatment: conventional drugs toward nanomedicine

被引：12
作者：
Azami, Sanaz Jafarpour [1 ,2 ]
Rahimi, Hanieh Mohammad [1 ]
Mirjalali, Hamed [1 ]
Zali, Mohammad Reza [3 ]
机构：
[1] Shahid Beheshti Univ Med Sci, Res Inst Gastroenterol & Liver Dis, Foodborne & Waterborne Dis Res Ctr, Tehran, Iran
[2] Univ Tehran Med Sci, Sch Publ Hlth, Dept Med Parasitol & Mycol, Tehran, Iran
[3] Shahid Beheshti Univ Med Sci, Res Inst Gastroenterol & Liver Dis, Gastroenterol & Liver Dis Res Ctr, Tehran, Iran
来源：
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY | 2021年 / 37卷 / 03期
关键词：
Toxoplasma gondii; Acute toxoplasmosis; Chronic toxoplasmosis; Treatment; Conventional therapy; Nanomedicine; CHITOSAN NANOPARTICLES; SILVER NANOPARTICLES; GONDII TACHYZOITES; ATOVAQUONE; NANOSILVER; INFECTION; MODEL;
D O I：
10.1007/s11274-021-03000-x
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Toxoplasma gondii is a worldwide protozoan parasite that infects almost all warm-blooded animals. Although human toxoplasmosis is mostly latent, pregnant women and immunocompromised patients need effective treatment. There are drugs of choice for treatment of toxoplasmosis; however, due to their side effects and/or their disease stage-specificity, prescription of them is limited. During recent years, nanomedicine has been employed to overcome limitations of conventional drugs. Here, we provided a state-of-the-art review of experimental toxoplasmosis treatment using nanotechnology.Graphic abstract
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页数：9
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