A convenient synthesis of chiral nonracemic vinyl aziridines

被引：86
|
作者：
Morton, D
Pearson, D
Field, RA
Stockman, RA [1 ]
机构：
[1] Univ E Anglia, Sch Chem Sci & Pharm, Norwich NR4 7TJ, Norfolk, England
[2] Millenium Pharmaceut UK, Cambridge CB1 6ET, England
来源：
ORGANIC LETTERS | 2004年 / 6卷 / 14期
基金：
英国生物技术与生命科学研究理事会;
关键词：
D O I：
10.1021/ol049252l
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The preparation of a range of alkyl and aryl chiral vinyl aziridines was achieved in high yield and stereoselectivity, and with excellent diastereoselectivity, by reaction of tert-butylsulfinylimines with the ylide derived from S-allyl tetrahydrothiophenium bromide.
引用
收藏
页码：2377 / 2380
页数：4
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