Sensors for detecting pulmonary diseases from exhaled breath

被引：78
作者：
Hashoul, Dina
Haick, Hossam
机构：
[1] Russell Berrie Nanotechnol Inst, Dept Chem Engn, Haifa, Israel
[2] Technion Integrated Canc Ctr, Haifa, Israel
来源：
EUROPEAN RESPIRATORY REVIEW | 2019年 / 28卷 / 152期
关键词：
VOLATILE ORGANIC-COMPOUNDS; ELECTRONIC NOSE TECHNOLOGY; OBSTRUCTIVE SLEEP-APNEA; LUNG-CANCER; COLORIMETRIC SENSOR; ARTERIAL-HYPERTENSION; NITRIC-OXIDE; DIAGNOSIS; DISCRIMINATION; TUBERCULOSIS;
D O I：
10.1183/16000617.0011-2019
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
This review presents and discusses a new frontier for fast, risk-free and potentially inexpensive diagnostics of respiratory diseases by detecting volatile organic compounds (VOCs) present in exhaled breath. One part of the review is a didactic presentation of the overlaying concept and the chemistry of exhaled breath. The other part discusses diverse sensors that have been developed and used for the detection of respiratory diseases (e.g. chronic obstructive pulmonary disease, asthma, lung cancer, pulmonary arterial hypertension, tuberculosis, cystic fibrosis, obstructive sleep apnoea syndrome and pneumoconiosis) by analysis of VOCs in exhaled breath. The strengths and pitfalls are discussed and criticised, particularly in the perspective in disseminating information regarding these advances. Ideas regarding the improvement of sensors, sensor arrays, sensing devices and the further planning of workflow are also discussed.
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页数：13
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