Facilitating oligonucleotide delivery: Helping antisense deliver on its promise - Commentary

被引:94
作者
Gewirtz, AM
Stein, CA
Glazer, PM
机构
[1] UNIV PENN, SCH MED, DEPT PATHOL, PHILADELPHIA, PA 19104 USA
[2] UNIV PENN, SCH MED, DEPT INTERNAL MED, PHILADELPHIA, PA 19104 USA
[3] UNIV PENN, SCH MED, INST HUMAN GENE THERAPY, PHILADELPHIA, PA 19104 USA
[4] COLUMBIA UNIV COLL PHYS & SURG, DEPT MED, DIV ONCOL, NEW YORK, NY 10032 USA
[5] YALE UNIV, SCH MED, BOYER CTR MOLEC MED, DEPT THERAPEUT RADIOL, NEW HAVEN, CT 06536 USA
关键词
D O I
10.1073/pnas.93.8.3161
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:3161 / 3163
页数:3
相关论文
共 33 条
[1]   RNA STRUCTURE - DESCRIBING THE ELEPHANT [J].
BASKERVILLE, S ;
ELLINGTON, AD .
CURRENT BIOLOGY, 1995, 5 (02) :120-123
[2]   2ND STRUCTURAL MOTIF FOR RECOGNITION OF DNA BY OLIGONUCLEOTIDE-DIRECTED TRIPLE-HELIX FORMATION [J].
BEAL, PA ;
DERVAN, PB .
SCIENCE, 1991, 251 (4999) :1360-1363
[3]   BINDING, UPTAKE, AND INTRACELLULAR TRAFFICKING OF PHOSPHOROTHIOATE-MODIFIED OLIGODEOXYNUCLEOTIDES [J].
BELTINGER, C ;
SARAGOVI, HU ;
SMITH, RM ;
LESAUTEUR, L ;
SHAH, N ;
DEDIONISIO, L ;
CHRISTENSEN, L ;
RAIBLE, A ;
JARETT, L ;
GEWIRTZ, AM .
JOURNAL OF CLINICAL INVESTIGATION, 1995, 95 (04) :1814-1823
[4]  
BENNETT CF, 1992, MOL PHARMACOL, V41, P1023
[5]   IMPROVED BIOLOGICAL-ACTIVITY OF ANTISENSE OLIGONUCLEOTIDES CONJUGATED TO A FUSOGENIC PEPTIDE [J].
BONGARTZ, JP ;
AUBERTIN, AM ;
MILHAUD, PG ;
LEBLEU, B .
NUCLEIC ACIDS RESEARCH, 1994, 22 (22) :4681-4688
[6]   A VERSATILE VECTOR FOR GENE AND OLIGONUCLEOTIDE TRANSFER INTO CELLS IN CULTURE AND IN-VIVO - POLYETHYLENIMINE [J].
BOUSSIF, O ;
LEZOUALCH, F ;
ZANTA, MA ;
MERGNY, MD ;
SCHERMAN, D ;
DEMENEIX, B ;
BEHR, JP .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (16) :7297-7301
[7]   INHIBITION OF LEUKEMIA-CELL PROLIFERATION BY RECEPTOR-MEDIATED UPTAKE OF C-MYB ANTISENSE OLIGODEOXYNUCLEOTIDES [J].
CITRO, G ;
PERROTTI, D ;
CUCCO, C ;
DAGNANO, I ;
SACCHI, A ;
ZUPI, G ;
CALABRETTA, B .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (15) :7031-7035
[8]  
CLARENC JP, 1993, ANTI-CANCER DRUG DES, V8, P81
[9]  
DEROSSI D, 1994, J BIOL CHEM, V269, P10444
[10]  
GAO WY, 1993, MOL PHARMACOL, V43, P45