Mathematical neuroscience: from neurons to circuits to systems

被引:39
|
作者
Gutkin, B [1 ]
Pinto, D [1 ]
Ermentrout, B [1 ]
机构
[1] Brown Univ, Div Biol & Med, Dept Neurosci, Providence, RI 02912 USA
关键词
mathematical models; non-linear dynamics; barrel cortex; spike-time statistics; hallucinations;
D O I
10.1016/j.jphysparis.2003.09.005
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Applications of mathematics and computational techniques to Our understanding Of neuronal systems are provided. Reduction of membrane models to simplified canonical models demonstrates how neuronal spike-time statistics follow from simple properties of neurons. Averaging over space allows one to derive a simple model for the whisker barrel circuit. and use this to explain and suggest several experiments. Spatio-temporal pattern formation methods are applied to explain the patterns seen in the early stages of drug-induced visual hallucinations. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:209 / 219
页数:11
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