Extravesical Pagetoid Spread of Urothelial Carcinoma in Situ A Report of Five Cases

被引:0
作者
Akgul, Mahmut [1 ]
Bomeisl, Phillip B. [1 ]
MacLennan, Gregory T. [1 ]
机构
[1] Univ Hosp Cleveland, Case Med Ctr, Dept Pathol, Cleveland, OH 44106 USA
来源
ANALYTICAL AND QUANTITATIVE CYTOPATHOLOGY AND HISTOPATHOLOGY | 2015年 / 37卷 / 06期
关键词
bladder; carcinoma in situ; cystoscopy; pagetoid spread; prostatic duct; seminal vesicles; urachus; urinary bladder; urothelial carcinoma; vagina; TRANSITIONAL-CELL CARCINOMA; URINARY-BLADDER; DISEASE; LESIONS;
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
BACKGROUND: Urothelial carcinoma in situ (CIS) of the bladder is classified as a flat lesion of the urothelium; it has a tendency to be multifocal and carries a high risk of recurrence and persistence. Approximately one-third of patients with urothelial CIS of the bladder develop invasive carcinoma if left untreated. There are a few reported cases of extravesical intramucosal extension (pagetoid spread) of urothelial CIS without prior documentation of primary muscle-invasive carcinoma. CASES: We present 5 cases of urothelial CIS that exhibited pagetoid spread to prostatic ducts, seminal vesicles, and the vagina. CONCLUSION: Pagetoid spread of urothelial CIS of the bladder may introduce uncertainty with regard to assignment of proper disease staging, and therefore uncertainty about appropriate cancer management.
引用
收藏
页码:364 / 368
页数:5
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